Inflammatory bowel disease (IBD) comprises ulcerative colitis (UC) and Crohn's disease
(CD). IBD etiopathology is multifactorial and involves alteration of immune cells and chronic …

Glucocorticoid hormones regulate essential body functions in mammals, control cell
metabolism, growth, differentiation, and apoptosis. Importantly, they are potent suppressors …

A key challenge for the effective treatment of gastrointestinal diseases including
inflammatory bowel disease is to develop an orally administered drug delivery system …

Since the discovery of glucocorticoids in the 1940s and the recognition of their anti-
inflammatory effects, they have been amongst the most widely used and effective treatments …

There is a clinical need for new, more effective treatments for chronic and debilitating
inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis …

Glucocorticoids are anti-inflammatory drugs that are widely used for the treatment of
numerous (autoimmune) inflammatory diseases. They exert their actions by binding to the …

Inflammation is a beneficial host reaction to tissue damage and has the essential primary
purpose of restoring tissue homeostasis. Inflammation plays a major role in containing and …

In this paper, we hypothesize that X chromosome‐associated mechanisms, which affect X‐
linked genes and are behind the immunological advantage of females, may also affect X …

Glucocorticoids (GCs) represent the mainstay of current anti‐inflammatory and
immunosuppressive strategies, mediating effects that mostly result in transcriptional …

For many decades, glucocorticoids have been widely used as the gold standard treatment
for inflammatory conditions. Unfortunately, their clinical use is limited by severe adverse …