[HTML][HTML] Enhancing the therapeutic efficacy of nanoparticles for cancer treatment using versatile targeted strategies

H Tian, T Zhang, S Qin, Z Huang, L Zhou, J Shi… - Journal of hematology & …, 2022 - Springer
Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …

[HTML][HTML] Oral delivery of RNAi for cancer therapy

H Afrin, R Geetha Bai, R Kumar, SS Ahmad… - Cancer and Metastasis …, 2023 - Springer
Cancer is a major health concern worldwide and is still in a continuous surge of seeking for
effective treatments. Since the discovery of RNAi and their mechanism of action, it has …

Delivery of engineered primary tumor-derived exosomes effectively suppressed the colorectal cancer chemoresistance and liver metastasis

C Huang, Y Zhou, X Feng, J Wang, Y Li, X Yao - ACS nano, 2023 - ACS Publications
Liver metastasis is one of the major causes of colorectal cancer (CRC)-related morbidity and
mortality. Delivering small interfering RNAs (siRNAs) or noncoding RNAs has been reported …

[HTML][HTML] Marine biomaterials in biomedical nano/micro-systems

Y Wang, L Chen, Y Wang, X Wang, D Qian… - Journal of …, 2023 - Springer
Marine resources in unique marine environments provide abundant, cost-effective natural
biomaterials with distinct structures, compositions, and biological activities compared to …

Combination of self-assembling system and N, O-carboxymethyl chitosan improves ocular residence of anti-glaucoma drug

V Kailasam, BN Kumara, KS Prasad, J Nirmal - European Journal of …, 2024 - Elsevier
Glaucoma is known to be one of the principal causes of vision loss due to elevated
intraocular pressure. Currently, latanoprost eye drops is used as first-line treatment for …

[HTML][HTML] Nanostructures for site-specific delivery of oxaliplatin cancer therapy: Versatile nanoplatforms in synergistic cancer therapy

M Bagheri, MA Zandieh, M Daryab, SS Samaei… - Translational …, 2024 - Elsevier
As a clinically approved treatment strategy, chemotherapy-mediated tumor suppression has
been compromised, and in spite of introducing various kinds of anticancer drugs, cancer …

Update on mucoadhesive approaches to target drug delivery in colorectal cancer

N Kanojia, K Thapa, N Verma, L Rani, P Sood… - Journal of Drug Delivery …, 2023 - Elsevier
Colorectal cancer (CRC) is indeed public health concern worldwide and refers to the
development of cancerous growth in the colon as well as the rectum. CRC is the third most …

High dose, dual-release polymeric films for extended surgical bed paclitaxel delivery

DA Mahvi, J Korunes-Miller, C Bordeianu… - Journal of Controlled …, 2023 - Elsevier
While surgery represents a major therapy for most solid organ cancers, local recurrence is
clinically problematic for cancers such as sarcoma for which adjuvant radiotherapy and …

Dissolvable layered microneedle patch containing 5-fluorouracil for localized treatment of oral carcinoma

A Matta, LSL Janardhanam, VVK Venuganti - Journal of Chemical …, 2023 - Springer
The matrix-forming microneedle-based drug delivery system has the potential to localize
drug dosage to the application site and limit systemic effects. Here, we report the …

[HTML][HTML] Nanotheranostics: platforms, current applications, and mechanisms of targeting in breast and prostate cancers

PA Akpa, IE Peter, AM Onwuka, BC Obi… - Journal of …, 2023 - mdpi.com
Globally, cancer is one of the deadliest diseases, needing a meticulous diagnosis and
targeted treatment plan to achieve an initial prognosis, followed by precision and …