Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …

Individuals suffering from severe viral respiratory tract infections have recently emerged as
“at risk” groups for developing invasive fungal infections. Influenza virus is one of the most …

Invariant natural killer T cells (iNKT cells) are an innate-like T cell subset that expresses an
invariant T cell receptor (TCR) α-chain and recognizes lipids presented on CD1d. They …

Although they are classically viewed as continuously recirculating through the lymphoid
organs and blood, lymphocytes also establish residency in non-lymphoid tissues, most …

Invariant natural killer T (iNKT) cells exist in a'poised effector'state, which enables them to
rapidly produce cytokines following activation. Using a nearly monospecific T cell receptor …

Immunity to pathogens critically requires pattern-recognition receptors (PRRs) to trigger
intracellular signaling cascades that initiate and direct innate and adaptive immune …

Administration of β-glucans through various routes, including immersion, dietary inclusion,
or injection, have been found to stimulate various facets of immune responses, such as …

In the last few decades, the AIDS pandemic and the significant advances in the medical
management of individuals with neoplastic and inflammatory conditions have resulted in a …

Over the past 15 years, investigators have shown that T lymphocytes can recognize not only
peptides in the context of MHC class I and class II molecules but also foreign and self-lipids …

Mucosa-associated invariant T (MAIT) cells are a unique population of αβ T cells in
mammals that reside preferentially in mucosal tissues and express an invariant Vα paired …