COVID-19-associated opportunistic infections: a snapshot on the current reports
Abstract Treatment of the novel Coronavirus Disease 2019 (COVID-19) remains a
complicated challenge, especially among patients with severe disease. In recent studies …
complicated challenge, especially among patients with severe disease. In recent studies …
Therapeutic potential of pyrrole and pyrrolidine analogs: an update
N Jeelan Basha, SM Basavarajaiah, K Shyamsunder - Molecular Diversity, 2022 - Springer
The chemistry of nitrogen-containing heterocyclic compound pyrrole and pyrrolidine has
been a versatile field of study for a long time for its diverse biological and medicinal …
been a versatile field of study for a long time for its diverse biological and medicinal …
[HTML][HTML] The central role of the nasal microenvironment in the transmission, modulation, and clinical progression of SARS-CoV-2 infection
The novel coronavirus SARS-CoV-2 enters into the human body mainly through the ACE2+
TMPRSS2+ nasal epithelial cells. The initial host response to this pathogen occurs in a …
TMPRSS2+ nasal epithelial cells. The initial host response to this pathogen occurs in a …
Interleukin-6, CXCL10 and infiltrating macrophages in COVID-19-related cytokine storm: not one for all but all for one!
F Coperchini, L Chiovato, M Rotondi - Frontiers in immunology, 2021 - frontiersin.org
SARS-COV-2 virus is responsible for the ongoing devastating pandemic. Since the early
phase of the pandemic, the “cytokine-storm” appeared a peculiar aspect of SARS-COV-2 …
phase of the pandemic, the “cytokine-storm” appeared a peculiar aspect of SARS-COV-2 …
[HTML][HTML] JAK inhibitors and COVID-19
G Levy, P Guglielmelli, P Langmuir… - … for immunotherapy of …, 2022 - ncbi.nlm.nih.gov
Abstract During SARS-CoV-2 infection, the innate immune response can be inhibited or
delayed, and the subsequent persistent viral replication can induce emergency signals that …
delayed, and the subsequent persistent viral replication can induce emergency signals that …
Liver injury in COVID-19 and IL-6 trans-signaling-induced endotheliopathy
MJ McConnell, N Kawaguchi, R Kondo, A Sonzogni… - Journal of …, 2021 - Elsevier
Background and Aims COVID-19 is associated with liver injury and elevated interleukin-6 (IL-
6). We hypothesized that IL-6 trans-signaling in liver sinusoidal endothelial cells (LSECs) …
6). We hypothesized that IL-6 trans-signaling in liver sinusoidal endothelial cells (LSECs) …
Immunotherapy of COVID-19: inside and beyond IL-6 signalling
G Zizzo, A Tamburello, L Castelnovo, A Laria… - Frontiers in …, 2022 - frontiersin.org
Acting on the cytokine cascade is key to preventing disease progression and death in
hospitalised patients with COVID-19. Among anti-cytokine therapies, interleukin (IL)-6 …
hospitalised patients with COVID-19. Among anti-cytokine therapies, interleukin (IL)-6 …
High mortality rate in COVID-19 patients with myeloproliferative neoplasms after abrupt withdrawal of ruxolitinib
T Barbui, AM Vannucchi, A Alvarez-Larran, A Iurlo… - Leukemia, 2021 - nature.com
We report the clinical presentation and risk factors for survival in 175 patients with
myeloproliferative neoplasms (MPN) and COVID-19, diagnosed between February and …
myeloproliferative neoplasms (MPN) and COVID-19, diagnosed between February and …
JAK inhibitors: Ten years after
Abstract The European Journal of Immunology was launched 50 years ago, coinciding with
the discovery of many cytokines and growth factors and the emergence of an entirely new …
the discovery of many cytokines and growth factors and the emergence of an entirely new …
Hallmarks of immune response in COVID-19: Exploring dysregulation and exhaustion
One and half year following the occurrence of COVID-19 pandemic, significant efforts from
laboratories all over the world generated a huge amount of data describing the prototypical …
laboratories all over the world generated a huge amount of data describing the prototypical …