Nanopharmaceuticals and nanomedicines currently on the market: challenges and opportunities

F Farjadian, A Ghasemi, O Gohari, A Roointan… - …, 2019 - Taylor & Francis
There has been a revolution in nanotechnology and nanomedicine. Since 1980, there has
been a remarkable increase in approved nano-based pharmaceutical products. These novel …

[HTML][HTML] Physicochemical properties of mucus and their impact on transmucosal drug delivery

J Leal, HDC Smyth, D Ghosh - International journal of pharmaceutics, 2017 - Elsevier
Mucus is a selective barrier to particles and molecules, preventing penetration to the
epithelial surface of mucosal tissues. Significant advances in transmucosal drug delivery …

Advances in drug delivery systems: Work in progress still needed?

F Laffleur, V Keckeis - International journal of pharmaceutics, 2020 - Elsevier
A new era of science and technology has emerged in pharmaceutical research with focus on
developing novel drug delivery systems for oral administration. Conventional dosage forms …

Lipid based nanocarriers: a translational perspective

DK Mishra, R Shandilya, PK Mishra - … : Nanotechnology, Biology and …, 2018 - Elsevier
Over the recent couple of decades, pharmaceutical field has embarked most phenomenal
noteworthy achievements in the field of medications as well as drug delivery. The rise of …

Nanoemulsions—advances in formulation, characterization and applications in drug delivery

SA Chime, FC Kenechukwu… - … of nanotechnology in drug …, 2014 - books.google.com
An ideal drug delivery system fulfils the objective of maximizing therapeutic effect while
minimizing toxicity. With the progress in time and advances in science and technology …

Plant-derived natural products in cancer research: extraction, mechanism of action, and drug formulation

WH Talib, I Alsalahat, S Daoud, RF Abutayeh… - Molecules, 2020 - mdpi.com
Cancer is one of the main causes of death globally and considered as a major challenge for
the public health system. The high toxicity and the lack of selectivity of conventional …

Self-nanoemulsifying drug delivery system (SNEDDS) with enhanced solubilization of nystatin for treatment of oral candidiasis: Design, optimization, in vitro and in …

AA Kassem, AM Mohsen, RS Ahmed… - Journal of molecular …, 2016 - Elsevier
The aim of the present study is to develop and optimize self-nanoemulsifying drug delivery
systems (SNEDDSs) to improve the per-oral bioavailability of poorly soluble polyene …

Solid self-nanoemulsifying drug delivery system (S-SNEDDS) of darunavir for improved dissolution and oral bioavailability: in vitro and in vivo evaluation

S Inugala, BB Eedara, S Sunkavalli, R Dhurke… - European Journal of …, 2015 - Elsevier
The current study was aimed to investigate the potential of solid self-nanoemulsifying drug
delivery system (S-SNEDDS) composed of Capmul MCM C8 (oil), Tween 80 (surfactant) and …

Synthesis of novel isoxazole–carboxamide derivatives as promising agents for melanoma and targeted nano-emulgel conjugate for improved cellular permeability

M Hawash, N Jaradat, AM Eid, A Abubaker, O Mufleh… - BMC chemistry, 2022 - Springer
Background Cancer is one of the most dangerous and widespread diseases in the world
today and it has risen to the position of the leading cause of death around the globe in the …

Recent trends of self-emulsifying drug delivery system for enhancing the oral bioavailability of poorly water-soluble drugs

P Tran, JS Park - Journal of Pharmaceutical Investigation, 2021 - Springer
Background The oral route is the most popular route for the clinical administration of drugs to
treat various diseases. Before a drug is absorbed into the blood circulation, it must undergo …