Effects of physical exercise on neuroinflammation, neuroplasticity, neurodegeneration, and behavior: what we can learn from animal models in clinical settings

M Svensson, J Lexell… - … and neural repair, 2015 - journals.sagepub.com
Physical exercise is a cornerstone in the management of many neurodegenerative
disorders, such as Parkinson's disease, dementia, and stroke. However, much of its …

Aerobic exercise: evidence for a direct brain effect to slow parkinson disease progression

JE Ahlskog - Mayo clinic proceedings, 2018 - Elsevier
No medications are proven to slow the progression of Parkinson disease (PD). Of special
concern with longer-standing PD is cognitive decline, as well as motor symptoms …

Voluntary exercise boosts striatal dopamine release: evidence for the necessary and sufficient role of BDNF

G Bastioli, JC Arnold, M Mancini, AC Mar… - Journal of …, 2022 - Soc Neuroscience
Physical exercise improves motor performance in individuals with Parkinson9s disease and
elevates mood in those with depression. Although underlying factors have not been …

Neuroprotective and symptomatic effects of cannabidiol in an animal model of Parkinson's disease

C Giuliano, M Francavilla, G Ongari, A Petese… - International Journal of …, 2021 - mdpi.com
Parkinson's disease (PD) is a neurodegenerative disorder characterized by the loss of
dopaminergic neurons in the Substantia Nigra pars compacta, leading to classical PD motor …

[图书][B] The clinical neuroscience of lateralization

A Mundorf, S Ocklenburg - 2021 - taylorfrancis.com
The Clinical Neuroscience of Lateralization gives the first comprehensive transdiagnostic
overview of the evidence for changes in hemispheric asymmetries in different psychiatric …

Neuroprotection and neurorestoration as experimental therapeutics for Parkinson's disease

V Francardo, Y Schmitz, D Sulzer, MA Cenci - Experimental neurology, 2017 - Elsevier
Disease-modifying treatments remain an unmet medical need in Parkinson's disease (PD).
Such treatments can be operationally defined as interventions that slow down the clinical …

[HTML][HTML] Time-course behavioral features are correlated with Parkinson's disease‑associated pathology in a 6-hydroxydopamine hemiparkinsonian rat model

RJ Su, JL Zhen, W Wang, JL Zhang… - Molecular …, 2018 - spandidos-publications.com
Parkinson's disease (PD) is one of the most common neurodegenerative diseases. For
decades, the unilateral 6‑hydroxydopamine (6‑OHDA) rat model has been employed to …

Exercise as a therapeutic intervention for motor and non-motor symptoms in Parkinson's disease: Evidence from rodent models

EK Crowley, YM Nolan, AM Sullivan - Progress in Neurobiology, 2019 - Elsevier
Parkinson's disease (PD) is characterised by degeneration of dopaminergic neurons of the
nigrostriatal pathway, which leads to the cardinal motor symptoms of the disease-tremor …

The effects of treadmill exercise in animal models of Parkinson's disease: A systematic review

AFF Ferreira, KH Binda, CC Real - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
Parkinson's disease (PD) is a progressive disabling brain disorder. Physical exercise has
been shown to alleviate the symptoms of PD and, consequently, improve patient quality of …

Rat models of vocal deficits in Parkinson's disease

MN Krasko, JD Hoffmeister, NE Schaen-Heacock… - Brain Sciences, 2021 - mdpi.com
Parkinson's disease (PD) is a progressive, degenerative disorder that affects 10 million
people worldwide. More than 90% of individuals with PD develop hypokinetic dysarthria, a …