Hepatitis C virus, a major human pathogen, produces infectious virus particles with several
unique features, such as an ability to interact with serum lipoproteins, a dizzyingly …

Hepatitis C virus (HCV) is a major global health burden accounting for around 170 million
chronic infections worldwide. Although highly potent direct-acting antiviral drugs to treat …

The Picornaviridae represent a large family of small plus-strand RNA viruses that cause a
bewildering array of important human and animal diseases. Morphogenesis is the least …

Hepatitis C virus (HCV) is among the most relevant causes of liver cirrhosis and
hepatocellular carcinoma. Research is complicated by a lack of accessible small animal …

More than 130 million people worldwide chronically infected with hepatitis C virus (HCV) are
at risk of developing severe liver disease. Antiviral treatments are only partially effective …

Apolipoprotein E (ApoE) is a multifunctional protein critical for lipid metabolism and
cholesterol homeostasis. In addition to being a well-known genetic determinant of both …

Hepatitis C virus (HCV) particles are known to be in complex with lipoproteins. As a result of
this interaction, the low‐density lipoprotein (LDL) receptor (LDLR) has been proposed as a …

Hepatitis C virus (HCV) is a leading cause of chronic liver disease, including chronic
hepatitis, fibrosis, cirrhosis, and hepatocellular carcinoma. Hepatitis C infection associates …

Primary human hepatocytes isolated from patient biopsies represent the most
physiologically relevant cell culture model for hepatitis C virus (HCV) infection, but these …

Abstract Hepatitis C Virus (HCV) particles exhibit several unusual properties that are not
found in other enveloped RNA viruses, most notably their low buoyant density and …