A neural substrate of prediction and reward

W Schultz, P Dayan, PR Montague - Science, 1997 - science.org
The capacity to predict future events permits a creature to detect, model, and manipulate the
causal structure of its interactions with its environment. Behavioral experiments suggest that …

The sympathetic nerve—an integrative interface between two supersystems: the brain and the immune system

IJ Elenkov, RL Wilder, GP Chrousos, ES Vizi - Pharmacological reviews, 2000 - ASPET
The brain and the immune system are the two major adaptive systems of the body. During
an immune response the brain and the immune system “talk to each other” and this process …

Polymorphisms of the 5'leader cistron of the human beta2-adrenergic receptor regulate receptor expression.

DW McGraw, SL Forbes, LA Kramer… - The Journal of clinical …, 1998 - Am Soc Clin Investig
Cellular expression of the beta2-adrenergic receptor (beta2AR) is controlled in part by a 19-
amino acid peptide that regulates mRNA translation. This peptide is encoded by a short …

The nuclear receptor PPAR gamma is expressed by mouse T lymphocytes and PPAR gamma agonists induce apoptosis

SG Harris, RP Phipps - European journal of immunology, 2001 - Wiley Online Library
Peroxisome proliferator‐activated receptor (PPAR)‐γ is a nuclear hormone receptor that
serves as a trans factor to regulate lipid metabolism. Intense interest is focused on PPAR‐γ …

Fatty acids and immune responses—a new perspective in searching for clues to mechanism

D Hwang - Annual review of nutrition, 2000 - annualreviews.org
Dietary essential fatty acids are the precursors for eicosanoids. Among the eicosanoids
derived from arachidonic acid, prostaglandin (PG) E2 is known to possess …

[HTML][HTML] Heterotrimeric G protein signaling: roles in immune function and fine-tuning by RGS proteins

JH Kehrl - Immunity, 1998 - cell.com
Immunologists hope to understand how extracellular stream signaling by G. Since G inhibits
guanine nuclesignals modulate and regulate the function of cells that otide dissociation …

A randomized controlled trial of the effect of pertussis vaccines on atopic disease

L Nilsson, M Kjellman, B Björkstén - Archives of pediatrics & …, 1998 - jamanetwork.com
Background Pertussis vaccination in infancy has been suggested to increase the risk for
development of asthma and allergy. Objective To assess sensitization rates and …

Schisandrin A ameliorates airway inflammation in model of asthma by attenuating Th2 response

Q Qiu, W Zhang, K Liu, F Huang, J Su, L Deng… - European Journal of …, 2023 - Elsevier
Asthma is a persistent respiratory ailment that displays periodicity and is linked to the
equilibrium of T cells. Several compounds obtained from Chinese herbal medicines display …

Phosphodiesterase 4B is essential for TH2-cell function and development of airway hyperresponsiveness in allergic asthma

SLC Jin, S Goya, S Nakae, D Wang, M Bruss… - Journal of allergy and …, 2010 - Elsevier
BACKGROUND: Cyclic AMP (cAMP) signaling modulates functions of inflammatory cells
involved in the pathogenesis of asthma, and type 4 cAMP-specific phosphodiesterases …

The β2-adrenergic agonist salbutamol is a potent suppressor of established collagen-induced arthritis: mechanisms of action

AM Malfait, AS Malik… - The Journal of …, 1999 - journals.aai.org
The therapeutic potential of salbutamol, a β 2-adrenergic agonist, was explored in collagen-
induced arthritis. This study was based on a report that salbutamol, by elevating intracellular …