Skeletal muscle contains a designated population of adult stem cells, called satellite cells,
which are generally quiescent. In homeostasis, satellite cells proliferate only sporadically …

Skeletal muscle has remarkable regeneration capabilities, mainly due to its resident muscle
stem cells (MuSCs). In this review, we introduce recently developed technologies and the …

Cachexia is the involuntary loss of muscle and adipose tissue that strongly affects mortality
and treatment efficacy in patients with cancer or chronic inflammatory disease. Currently, no …

During ageing, muscle stem-cell regenerative function declines. At advanced geriatric age,
this decline is maximal owing to transition from a normal quiescence into an irreversible …

Regeneration of skeletal muscle depends on a population of adult stem cells (satellite cells)
that remain quiescent throughout life. Satellite cell regenerative functions decline with …

Interleukin (IL)‐6 is a cytokine with pleiotropic functions in different tissues and organs.
Skeletal muscle produces and releases significant levels of IL‐6 after prolonged exercise …

Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase (MAPK) family
members function in a cell context-specific and cell type-specific manner to integrate signals …

Mammalian p38 mitogen-activated protein kinases (MAPKs) are activated by a wide range
of cellular stresses as well as in response to inflammatory cytokines. There are four …

Skeletal muscles adapt to increasing workload by augmenting their fiber size, through
mechanisms that are poorly understood. This study identifies the cytokine interleukin-6 (IL-6) …

Research focusing on the canonical adult myogenic progenitor, the skeletal muscle satellite
cell, is still an ever-growing field 46 years from their initial description. Recent publications …