Aging is characterized by a progressive deterioration of physiological integrity, leading to
impaired functional ability and ultimately increased susceptibility to death. It is a major risk …

The ageing process is a systemic decline from cellular dysfunction to organ degeneration,
with more predisposition to deteriorated disorders. Rejuvenation refers to giving aged cells …

Cancer is one of the leading causes of death worldwide. Human cytomegalovirus (HCMV), a
well-studied herpesvirus, has been implicated in malignancies derived from breast …

Life expectancy has drastically increased over the last few decades worldwide, with
important social and medical burdens and costs. To stay healthy longer and to avoid chronic …

Simple Summary Age-related cardiovascular disease is the foremost cause of death
globally. Despite medical advances, we have been unable to stop or reverse the underlying …

Aging can be defined as a functional decline in the physiological integrity of a living
organism over time. It can lead to disruption in homeostasis not only at the whole organism …

Telomerase preserves genomic integrity by maintaining and protecting the telomeres.
Seminal findings from 1985 revealed the canonical role of telomerase and motivated …

Viral vectors have emerged as powerful tools for delivering and expressing foreign genes,
playing a pivotal role in gene therapy. Among these vectors, cytomegalovirus (CMV) stands …

Aging entails gradual functional decline influenced by interconnected factors. Multiple
hallmarks proposed as common and conserved underlying denominators of aging on the …

2 Materials and methods We crossed mice expressing Cre under the control of EC-specific
Tie2e promoter (Kano et al., 2003) with TERT fl/fl mice also carrying the mTmG reporter …