Neurological disorders significantly outnumber diseases in other therapeutic areas.
However, developing drugs for central nervous system (CNS) disorders remains the most …

Ultrasound sensitivity to slow blood flow motion gained two orders of magnitude in the last
decade thanks to the advent of ultrafast ultrasound imaging at thousands of frames per …

Functional ultrasound (fUS) is a neuroimaging method that uses ultrasound to track changes
in cerebral blood volume as an indirect readout of neuronal activity at high spatiotemporal …

Functional ultrasound (fUS) is an emerging neuroimaging tool capable of measuring brain-
wide vascular signals linked to neuronal activity with high spatial–temporal resolution in real …

Neurological disorders affect various aspects of life. Finding drugs for the central nervous
system is a very challenging and complex task due to the involvement of the blood–brain …

Introduction S-ketamine has received great interest due to both its antidepressant effects
and its potential to induce psychosis when administered subchronically. However, no …

Translational methods are needed to monitor the impact of the Alzheimer's disease (AD) and
therapies on brain function in animal models and patients. The formation of amyloid plaques …

Central nervous system disorders remain the leading causes of mortality and morbidity
worldwide, affecting more than 1 billion patients. This therapeutic area suffers from high …

Background: There is an urgent need to understand and reverse cognitive impairment. The
lack of appropriate animal models combined with the limited knowledge of …

Autophagy is a process leading to the degradation of cellular material, in organelles called
lysosomes, to supply energy or generate building blocks for the synthesis of new materials …