Advances in point-of-care nucleic acid extraction technologies for rapid diagnosis of human and plant diseases

R Paul, E Ostermann, Q Wei - Biosensors and bioelectronics, 2020 - Elsevier
Global health and food security constantly face the challenge of emerging human and plant
diseases caused by bacteria, viruses, fungi, and other pathogens. Disease outbreaks such …

Advanced “lab-on-a-chip” to detect viruses–Current challenges and future perspectives

J Zhuang, J Yin, S Lv, B Wang, Y Mu - Biosensors and Bioelectronics, 2020 - Elsevier
Massive viral outbreaks draw attention to viruses that have not been thoroughly studied or
understood. In recent decades, microfluidic chips, known as “lab-on-a-chip”, appears as a …

Integrated microfluidic systems with sample preparation and nucleic acid amplification

J Yin, Y Suo, Z Zou, J Sun, S Zhang, B Wang, Y Xu… - Lab on a Chip, 2019 - pubs.rsc.org
Rapid, efficient and accurate nucleic acid molecule detection is important in the screening of
diseases and pathogens, yet remains a limiting factor at point of care (POC) treatment …

COVID-19 pandemic: review of contemporary and forthcoming detection tools

MJ Oishee, T Ali, N Jahan, SS Khandker… - Infection and drug …, 2021 - Taylor & Francis
Recent severe acute respiratory syndrome 2 (SARS-CoV-2) known as COVID-19, presents a
deadly challenge to the global healthcare system of developing and developed countries …

Dengue detection: advances in diagnostic tools from conventional technology to point of care

MA Kabir, H Zilouchian, MA Younas, W Asghar - Biosensors, 2021 - mdpi.com
The dengue virus (DENV) is a vector-borne flavivirus that infects around 390 million
individuals each year with 2.5 billion being in danger. Having access to testing is paramount …

[HTML][HTML] Pathogen detection on microfluidic platforms: Recent advances, challenges, and prospects

A Jagannath, H Cong, J Hassan, G Gonzalez… - … and Bioelectronics: X, 2022 - Elsevier
Abstract Point-Of-Care (POC) testing has advanced to more affordable and rapid
alternatives by adapting conventional immunoassays and molecular assays (isothermal …

A self-priming digital polymerase chain reaction chip for multiplex genetic analysis

J Yin, Z Zou, F Yin, H Liang, Z Hu, W Fang, S Lv… - Acs Nano, 2020 - ACS Publications
Digital PCR (polymerase chain reaction) is a powerful and attractive tool for the
quantification of nucleic acids. However, the multiplex detection capabilities of this system …

Recent advances and application of whole genome amplification in molecular diagnosis and medicine

X Wang, Y Liu, H Liu, W Pan, J Ren, X Zheng… - MedComm, 2022 - Wiley Online Library
Whole genome amplification (WGA) is a technology for non‐selective amplification of the
whole genome sequence, first appearing in 1992. Its primary purpose is to amplify and …

An overview on microfluidic systems for nucleic acids extraction from human raw samples

D Obino, M Vassalli, A Franceschi, A Alessandrini… - Sensors, 2021 - mdpi.com
Nucleic acid (NA) extraction is a basic step for genetic analysis, from scientific research to
diagnostic and forensic applications. It aims at preparing samples for its application with …

A self-contained and fully integrated fluidic cassette system for multiplex nucleic acid detection of bacteriuria

N Li, Y Lu, J Cheng, Y Xu - Lab on a Chip, 2020 - pubs.rsc.org
The gold standard for diagnosing infectious diseases is culture-based identification of
bacterial pathogens, which is time-consuming and labour-intensive. Current advances in …