Advances in point-of-care nucleic acid extraction technologies for rapid diagnosis of human and plant diseases
Global health and food security constantly face the challenge of emerging human and plant
diseases caused by bacteria, viruses, fungi, and other pathogens. Disease outbreaks such …
diseases caused by bacteria, viruses, fungi, and other pathogens. Disease outbreaks such …
Advanced “lab-on-a-chip” to detect viruses–Current challenges and future perspectives
J Zhuang, J Yin, S Lv, B Wang, Y Mu - Biosensors and Bioelectronics, 2020 - Elsevier
Massive viral outbreaks draw attention to viruses that have not been thoroughly studied or
understood. In recent decades, microfluidic chips, known as “lab-on-a-chip”, appears as a …
understood. In recent decades, microfluidic chips, known as “lab-on-a-chip”, appears as a …
Integrated microfluidic systems with sample preparation and nucleic acid amplification
J Yin, Y Suo, Z Zou, J Sun, S Zhang, B Wang, Y Xu… - Lab on a Chip, 2019 - pubs.rsc.org
Rapid, efficient and accurate nucleic acid molecule detection is important in the screening of
diseases and pathogens, yet remains a limiting factor at point of care (POC) treatment …
diseases and pathogens, yet remains a limiting factor at point of care (POC) treatment …
COVID-19 pandemic: review of contemporary and forthcoming detection tools
Recent severe acute respiratory syndrome 2 (SARS-CoV-2) known as COVID-19, presents a
deadly challenge to the global healthcare system of developing and developed countries …
deadly challenge to the global healthcare system of developing and developed countries …
Dengue detection: advances in diagnostic tools from conventional technology to point of care
The dengue virus (DENV) is a vector-borne flavivirus that infects around 390 million
individuals each year with 2.5 billion being in danger. Having access to testing is paramount …
individuals each year with 2.5 billion being in danger. Having access to testing is paramount …
[HTML][HTML] Pathogen detection on microfluidic platforms: Recent advances, challenges, and prospects
Abstract Point-Of-Care (POC) testing has advanced to more affordable and rapid
alternatives by adapting conventional immunoassays and molecular assays (isothermal …
alternatives by adapting conventional immunoassays and molecular assays (isothermal …
A self-priming digital polymerase chain reaction chip for multiplex genetic analysis
J Yin, Z Zou, F Yin, H Liang, Z Hu, W Fang, S Lv… - Acs Nano, 2020 - ACS Publications
Digital PCR (polymerase chain reaction) is a powerful and attractive tool for the
quantification of nucleic acids. However, the multiplex detection capabilities of this system …
quantification of nucleic acids. However, the multiplex detection capabilities of this system …
Recent advances and application of whole genome amplification in molecular diagnosis and medicine
X Wang, Y Liu, H Liu, W Pan, J Ren, X Zheng… - MedComm, 2022 - Wiley Online Library
Whole genome amplification (WGA) is a technology for non‐selective amplification of the
whole genome sequence, first appearing in 1992. Its primary purpose is to amplify and …
whole genome sequence, first appearing in 1992. Its primary purpose is to amplify and …
An overview on microfluidic systems for nucleic acids extraction from human raw samples
D Obino, M Vassalli, A Franceschi, A Alessandrini… - Sensors, 2021 - mdpi.com
Nucleic acid (NA) extraction is a basic step for genetic analysis, from scientific research to
diagnostic and forensic applications. It aims at preparing samples for its application with …
diagnostic and forensic applications. It aims at preparing samples for its application with …
A self-contained and fully integrated fluidic cassette system for multiplex nucleic acid detection of bacteriuria
N Li, Y Lu, J Cheng, Y Xu - Lab on a Chip, 2020 - pubs.rsc.org
The gold standard for diagnosing infectious diseases is culture-based identification of
bacterial pathogens, which is time-consuming and labour-intensive. Current advances in …
bacterial pathogens, which is time-consuming and labour-intensive. Current advances in …