Catalytic asymmetric 1, 3-dipolar cycloadditions of azomethine ylides have turned out to be
one of the most efficient methods for the preparation of enantioenriched pyrrolidines. The …

The preparation of chiral compounds is an important and challenging area of contemporary
synthetic organic chemistry. 1 The 1, 3-dipolar cycloaddition, also known as the Huisgen …

The discovery of nonproteinogenic amino acids among natural products, either in native
state or as fragments of complex molecules, has increased the level of interest in this family …

With modern methods for asymmetric catalysis breaking ground, the use of chiral auxiliaries
seems to be old-fashioned and rather inefficient. However, for many transformations, chiral …

Abstract (Chemical Equation Presented) Optically active α, β-diamino acids are prepared
under asymmetric phase-transfer reaction conditions from a glycine Schiff base and N …

A palladium-catalyzed asymmetric [3+ 2] annulation reaction between racemic 5-
vinyloxazolidinones and N-sulfonyl imines was established. Under the influence of the …

Direct Assembly of Aldehydes, Amino Esters, and Anilines into Chiral Imidazolidines via
Brønsted Acid Catalyzed Asymmetric 1,3-Dipolar Cycloadditions | Organic Letters ACS ACS …

An easily available L-proline-derived guanidine-amide was found to be efficient at
catalyzing a [4+ 2] cycloaddition of azlactones with 2-benzothiazolimines, affording various …

The important requirement for approval of a new drug, in case it happens to be chiral, is that
both enantiomers of the drug should be studied in detail, which has led synthetic organic …

A new “single‐flask” method was developed for the synthesis of imidazolidines and
pyrrolidines with high stereoselectivity. First, a Schiff base was arylated with an aryne …