Obesity and bone: a complex relationship

G Rinonapoli, V Pace, C Ruggiero, P Ceccarini… - International journal of …, 2021 - mdpi.com
There is a large literature on the relationship between obesity and bone. What we can
conclude from this review is that the increase in body weight causes an increase in BMD …

Dietary weight-loss interventions for the management of obesity in older adults

S Goisser, E Kiesswetter, D Schoene… - Reviews in Endocrine …, 2020 - Springer
The obesity epidemic has reached old age in most industrialized countries, but trials
elucidating the benefits and risks of weight reduction in older adults above 70 years of age …

Effect of exercise modality during weight loss on bone health in older adults with obesity and cardiovascular disease or metabolic syndrome: a randomized controlled …

KM Beavers, MP Walkup, AA Weaver… - Journal of Bone and …, 2018 - academic.oup.com
The objective of this study was to determine the ability of either aerobic or resistance training
to counter weight‐loss‐associated bone loss in older adults. There were 187 older adults …

Weight loss-induced reduction of bone mineral density in older adults with obesity

BC Jiang, DT Villareal - Journal of nutrition in gerontology and …, 2019 - Taylor & Francis
Obesity in older adults is a growing public health problem, yet the appropriate treatment
remains controversial partly due to evidence that weight loss reduces bone mass and may …

Bone response to weight loss following bariatric surgery

C Mele, M Caputo, A Ferrero, T Daffara… - Frontiers in …, 2022 - frontiersin.org
Obesity is a global health challenge that warrants effective treatments to avoid its multiple
comorbidities. Bariatric surgery, a cornerstone treatment to control bodyweight excess and …

Is weight loss harmful for skeletal health in obese older adults?

M Papageorgiou, K Kerschan-Schindl, T Sathyapalan… - Gerontology, 2020 - karger.com
Abstract Purpose of Review: In view of the existing uncertainty about the implications of
intentional weight loss in older obese adults, the present review (a) summarizes the …

Beneficial impact of exercise on bone mass in individuals under calorie restriction: a systematic review and Meta-analysis of randomized clinical trials

H Yarizadeh, S Asadi, H Baharlooi… - Critical reviews in …, 2021 - Taylor & Francis
Background: A major therapeutic goal in weight management should be total body fat
reduction whereas as preserving lean body mass and bone mass density. It is uncertain if an …

Risedronate to prevent bone loss after sleeve gastrectomy: study design and feasibility report of a pilot randomized controlled trial

AA Swafford, JD Ard, DP Beavers… - Journal of Bone and …, 2020 - academic.oup.com
Mounting evidence implicates bariatric surgery as a cause of increased skeletal fragility and
fracture risk. Bisphosphonate therapy reduces osteoporotic fracture risk and may be effective …

Studies in microgravity, simulated microgravity and gravity do not support a gravitostat

RT Turner, AJ Branscum, CP Wong… - Journal of …, 2020 - joe.bioscientifica.com
The gravitostat is purported to function as a leptin-independent, osteocyte-dependent
mechanism for regulation of energy balance. If correct, reduced activation of gravitostat …

Incorporating nutrition, vests, education, and strength training (invest) in bone health: Trial design and methods

RM Miller, DP Beavers, PM Cawthon, C Crotts… - Contemporary clinical …, 2021 - Elsevier
Abstract Background Achievement of 5–10% weight loss (WL) among older adults living with
obesity considerably improves prognosis of health-related outcomes; however, concomitant …