A disinhibitory circuit mechanism explains a general principle of peak performance during mid-level arousal

L Beerendonk, JF Mejías, SA Nuiten… - Proceedings of the …, 2024 - National Acad Sciences
Perceptual decision-making is highly dependent on the momentary arousal state of the
brain, which fluctuates over time on a scale of hours, minutes, and even seconds. The …

Optimal heterogeneity for coding in spiking neural networks

JF Mejias, A Longtin - Physical Review Letters, 2012 - APS
The effect of cellular heterogeneity on the coding properties of neural populations is studied
analytically and numerically. We find that heterogeneity decreases the threshold for …

Functional subtypes of synaptic dynamics in mouse and human

J Beninger, J Rossbroich, K Tóth, R Naud - Cell Reports, 2024 - cell.com
Synapses preferentially respond to particular temporal patterns of activity with a large
degree of heterogeneity that is informally or tacitly separated into classes. Yet, the precise …

Double inverse stochastic resonance with dynamic synapses

M Uzuntarla, JJ Torres, P So, M Ozer, E Barreto - Physical Review E, 2017 - APS
We investigate the behavior of a model neuron that receives a biophysically realistic noisy
postsynaptic current based on uncorrelated spiking activity from a large number of afferents …

Differential effects of excitatory and inhibitory heterogeneity on the gain and asynchronous state of sparse cortical networks

JF Mejias, A Longtin - Frontiers in computational neuroscience, 2014 - frontiersin.org
Recent experimental and theoretical studies have highlighted the importance of cell-to-cell
differences in the dynamics and functions of neural networks, such as in different types of …

Flexible metal oxide synaptic transistors using biomass-based hydrogel as gate dielectric

J Chen, E Li, Y Yan, Q Yang, S Cao… - Journal of Physics D …, 2019 - iopscience.iop.org
The construction of devices with biocompatible and biodegradable materials is a
sustainable approach which will open up a new way for the development of green …

Neural correlates of multisensory detection behavior: comparison of primary and higher-order visual cortex

GT Meijer, P Marchesi, JF Mejias, JS Montijn… - Cell reports, 2020 - cell.com
We act upon stimuli in our surrounding environment by gathering the multisensory
information they convey and by integrating this information to decide on a behavioral action …

Emergence of resonances in neural systems: the interplay between adaptive threshold and short-term synaptic plasticity

JF Mejias, JJ Torres - PloS one, 2011 - journals.plos.org
In this work we study the detection of weak stimuli by spiking (integrate-and-fire) neurons in
the presence of certain level of noisy background neural activity. Our study has focused in …

Irregular dynamics in up and down cortical states

JF Mejias, HJ Kappen, JJ Torres - PLoS One, 2010 - journals.plos.org
Complex coherent dynamics is present in a wide variety of neural systems. A typical
example is the voltage transitions between up and down states observed in cortical areas in …

Maximum memory capacity on neural networks with short-term synaptic depression and facilitation

JF Mejias, JJ Torres - Neural computation, 2009 - direct.mit.edu
In this work, we study, analytically and employing Monte Carlo simulations, the influence of
the competition between several activity-dependent synaptic processes, such as short-term …