[HTML][HTML] Optical coherence tomography angiography

RF Spaide, JG Fujimoto, NK Waheed, SR Sadda… - Progress in retinal and …, 2018 - Elsevier
Optical coherence tomography (OCT) was one of the biggest advances in ophthalmic
imaging. Building on that platform, OCT angiography (OCTA) provides depth resolved …

[HTML][HTML] The progression of geographic atrophy secondary to age-related macular degeneration

M Fleckenstein, P Mitchell, KB Freund, SV Sadda… - Ophthalmology, 2018 - Elsevier
Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD)
that leads to progressive and irreversible loss of visual function. Geographic atrophy is …

Age-related macular degeneration: etiology, pathogenesis, and therapeutic strategies

J Ambati, BK Ambati, SH Yoo, S Ianchulev… - Survey of …, 2003 - Elsevier
Age-related macular degeneration is the principal cause of registered legal blindness
among those aged over 65 in the United States, western Europe, Australia, and Japan …

NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components

SL Doyle, M Campbell, E Ozaki, RG Salomon, A Mori… - Nature medicine, 2012 - nature.com
Age-related macular degeneration (AMD) is the leading cause of central vision loss
worldwide. Drusen accumulation is the major pathological hallmark common to both dry and …

Current concepts in the pathogenesis of age-related macular degeneration

MA Zarbin - Archives of ophthalmology, 2004 - jamanetwork.com
Objective To review and synthesize information concerning the pathogenesis ofage-related
macular degeneration (AMD). Methods Review of the English-language literature. Results …

The epidemiology of age-related macular degeneration

R Klein, T Peto, A Bird, MR Vannewkirk - American journal of …, 2004 - Elsevier
PURPOSE: To review the epidemiology of age-related macular degeneration (AMD).
DESIGN: Evidence from epidemiologic data regarding the natural history of AMD and its risk …

Age‐related macular degeneration—emerging pathogenetic and therapeutic concepts

KM Gehrs, DH Anderson, LV Johnson… - Annals of …, 2006 - Taylor & Francis
Today, the average life expectancy in developed nations is over 80 years and climbing. And
yet, the quality of life during those additional years is often significantly diminished by the …

[HTML][HTML] Dry age-related macular degeneration: mechanisms, therapeutic targets, and imaging

CB Rickman, S Farsiu, CA Toth… - … ophthalmology & visual …, 2013 - jov.arvojournals.org
Age-related macular degeneration is the leading cause of irreversible visual dysfunction in
individuals over 65 in Western Society. Patients with AMD are classified as having early …

Fundus autofluorescence imaging

S Schmitz-Valckenberg, M Pfau, M Fleckenstein… - Progress in retinal and …, 2021 - Elsevier
Fundus autofluorescence (FAF) imaging is an in vivo imaging method that allows for
topographic mapping of naturally or pathologically occurring intrinsic fluorophores of the …

Exploring the pathogenesis of age-related macular degeneration: A review of the interplay between retinal pigment epithelium dysfunction and the innate immune …

JHC Wong, JYW Ma, AI Jobling, A Brandli… - Frontiers in …, 2022 - frontiersin.org
Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss in the
older population. Classical hallmarks of early and intermediate AMD are accumulation of …