Modifications of RNA affect its function and stability. RNA editing is unique among these
modifications because it not only alters the cellular fate of RNA molecules but also alters …

The chemical identity of RNA molecules beyond the four standard ribonucleosides has
fascinated scientists since pseudouridine was characterized as the “fifth” ribonucleotide in …

We present RADAR—a rigorously annotated database of A-to-I RNA editing (available at
http://RNAedit. com). The identification of A-to-I RNA editing sites has been dramatically …

Summary Adenosine-to-inosine (A-to-I) RNA editing is a widespread post-transcriptional
mechanism, but its genomic landscape and clinical relevance in cancer have not been …

Identifying genomic variation is a crucial step for unraveling the relationship between
genotype and phenotype and can yield important insights into human diseases. Prevailing …

We show that RNA editing sites can be called with high confidence using RNA sequencing
data from multiple samples across either individuals or species, without the need for …

One of the most prevalent forms of post-transcritpional RNA modification is the conversion of
adenosine nucleosides to inosine (A-to-I), mediated by the ADAR family of enzymes. The …

As a means to understand human neuropsychiatric disorders from human brain samples, we
compared the transcription patterns and histological features of postmortem brain to fresh …

The coleoid cephalopods have the largest brains, and display the most complex behaviors,
of all invertebrates. The molecular and cellular mechanisms that underlie these remarkable …

The mitochondrial ribosome, which translates all mitochondrial DNA (mtDNA)-encoded
proteins, should be tightly regulated pre-and post-transcriptionally. Recently, we found RNA …