Cancer is a severe public health issue that is a leading cause of mortality globally. It is also
an impediment to improving life expectancy worldwide. Furthermore, the global burden of …

Biological entities are involved in intricate and complex interactions, in which uncovering the
biological information from the network concepts are of great significance. Benefiting from …

The identification of gene fusions from RNA sequencing data is a routine task in cancer
research and precision oncology. However, despite the availability of many computational …

Background Capivasertib, an AKT inhibitor, added to fulvestrant, was previously reported to
improve progression-free survival in women with aromatase inhibitor-resistant oestrogen …

Background Copper ions are essential for cellular physiology. Cuproptosis is a novel
method of copper-dependent cell death, and the cuproptosis-based signature for glioma …

Identifying molecular cancer drivers is critical for precision oncology. Multiple advanced
algorithms to identify drivers now exist, but systematic attempts to combine and optimize …

DNA methylation plays a critical role in establishing and maintaining cellular identity.
However, it is frequently dysregulated during tumor development and is closely intertwined …

Mature T-cell lymphomas, including peripheral T-cell lymphoma (PTCL) and extranodal
NK/T-cell lymphoma (NKTL), represent a heterogeneous group of non-Hodgkin lymphomas …

The epidermal growth factor receptor (EGFR) is frequently mutated in human cancer,, and is
an important therapeutic target. EGFR inhibitors have been successful in lung cancer, where …

Glioblastoma is a universally lethal form of brain cancer that exhibits an array of
pathophysiological phenotypes, many of which are mediated by interactions with the …