Normal eating behaviour is coordinated by the tightly regulated balance between intestinal
and extra-intestinal homeostatic and hedonic mechanisms. By contrast, food addiction is a …

Obesity is a complex, chronic medical condition with a major negative impact on human
health. 1 Over the last 30 years, there has been an exponential growth in the prevalence of …

Childhood obesity is one of the most serious public health chal-lenges of this century.
Overweight and obese children are likely to stay obese into adulthood and more likely to …

Context Recent studies show that dietary habits and obesity seem to be influenced by
chronotype, which reflects an individual's preference for the timing of sleeping, eating, and …

The cloning of leptin in 1994 was an important milestone in obesity research. In those days
obesity was stigmatized as a condition caused by lack of character and self-control …

Food is a potent natural reward and food intake is a complex process. Reward and
gratification associated with food consumption leads to dopamine (DA) production, which in …

Hypothalamic-pituitary-gonadal (HPG) axis function fundamentally affects the physiology of
eating. We review sex differences in the physiological and pathophysiological controls of …

Background 'Food addiction'shares a similar neurobiological and behavioral framework with
substance addiction. However whether, and to what degree,'food addiction'contributes to …

Our gut harbours trillions of microorganisms essential for the maintenance of homeostasis
and host physiology in health and disease. In the last decade, there has been a growing …

In November 1955, Geoffrey Harris published a paper based on the Christian A Herter
Lecture he had given earlier that year at Johns Hopkins University in Baltimore, MD, USA …