Ghrelin, an acylated peptide hormone of 28 amino acids, is an endogenous ligand of the
released growth hormone secretagogue receptor (GHSR). Ghrelin has been isolated from …

Ghrelin is the only known peripherally-derived orexigenic hormone, increasing appetite and
subsequent food intake. The ghrelinergic system has therefore received considerable …

Endocrine disrupting chemicals (EDCs) have widespread environmental distribution
originated from both natural and anthropogenic sources. From the last few decades, their …

Ghrelin is a metabolic hormone that promotes energy conservation by regulating appetite
and energy expenditure. Although some studies suggest that antagonizing ghrelin function …

Much effort has been directed at studying the orexigenic actions of administered ghrelin and
the potential effects of the endogenous ghrelin system on food intake, food reward, body …

Ever since Claude Bernards discovery in the mid 19th-century that a lesion in the floor of the
third ventricle in dogs led to altered systemic glucose levels, a role of the CNS in whole-body …

Context Altered satiety hormones in women with polycystic ovarian syndrome (PCOS) may
contribute to obesity. Diets with a low glycemic load (GL) may influence appetite-regulating …

Liver-expressed antimicrobial peptide 2 (LEAP2) is a newly discovered antagonist of the
growth hormone secretagogue receptor (GHSR) and is considered the first endogenous …

The stomach-derived hormone ghrelin regulates essential physiological functions. The
ghrelin receptor (GHSR) has ligand-independent actions; therefore, GHSR gene deletion …

The underlying mechanisms for the development and progression of nonalcoholic fatty liver
disease (NAFLD) are complex and multifactorial. Within the last years, experimental and …