Tumour necrosis factor-α (TNF) is a multifunctional cytokine. First recognized as an
endogenous soluble factor that induces necrosis of solid tumours, TNF became increasingly …

The risk of colorectal cancer (CRC) is higher in patients with inflammatory bowel disease
(IBD). Population-based data from patients with ulcerative colitis (UC) estimate that the risk …

Summary T helper 17 (Th17) cells are pathogenic in many inflammatory diseases, but also
support the integrity of the intestinal barrier in a non-inflammatory manner. It is unclear what …

Autoimmune diseases (such as rheumatoid arthritis, asthma, autoimmune bowel disease)
are a complex disease. Improper activation of the immune system or imbalance of immune …

Colorectal cancer is the third largest cancer in worldwide and has been proven to be closely
related to the intestinal microbiota. Many reports and clinical studies have shown that …

Ulcerative colitis (UC), a nonspecific inflammatory disease, is characterized by inflammation
and mucosal damage in the colon, and its prevalence in the world is increasing …

The human gut microbiota has been the interest of extensive research in recent years and
our knowledge on using the potential capacity of these microbes are growing rapidly …

Formerly considered as a passive process, the resolution of acute inflammation is now
recognized as an active host response, with a cascade of coordinated cellular and …

Modulation of the gut microbiome as a means to improve human health has recently gained
increasing interest. In this study, it was investigated whether cRG-I, a carrot-derived pectic …

Gastrointestinal complaints are often reported during ascents to high altitude (> 2,500 m),
though their etiology is not known. One potential explanation is injury to the intestinal barrier …