The introduction of in vitro nucleic acid amplification techniques, led by real-time PCR, into
the clinical microbiology laboratory has transformed the laboratory detection of viruses and …

Microfluidic devices possess many advantages like high throughput, short analysis time,
small volume and high sensitivity that fulfill all the important criteria of an immunoassay used …

Illumina microarray is becoming a popular microarray platform. The BeadArray technology
from Illumina makes its preprocessing and quality control different from other microarray …

Extensive studies are currently being performed to associate disease susceptibility with one
form of genetic variation, namely, single-nucleotide polymorphisms (SNPs). In recent years …

The genetic basis of gene expression variation has long been studied with the aim to
understand the landscape of regulatory variants, but also more recently to assist in the …

Genetic variation influences gene expression, and this variation in gene expression can be
efficiently mapped to specific genomic regions and variants. Here we have used gene …

Human pluripotent stem cells (hPSCs) are potential sources of cells for modeling disease
and development, drug discovery, and regenerative medicine. However, it is important to …

Background The 4T1 mouse mammary tumor cell line is one of only a few breast cancer
models with the capacity to metastasize efficiently to sites affected in human breast cancer …

Variance stabilization is a step in the preprocessing of microarray data that can greatly
benefit the performance of subsequent statistical modeling and inference. Due to the often …

The R/Bioconductor package beadarray allows raw data from Illumina experiments to be
read and stored in convenient R classes. Users are free to choose between various methods …