Role of chemokine systems in cancer and inflammatory diseases
H Li, M Wu, X Zhao - MedComm, 2022 - Wiley Online Library
Chemokines are a large family of small secreted proteins that have fundamental roles in
organ development, normal physiology, and immune responses upon binding to their …
organ development, normal physiology, and immune responses upon binding to their …
Mechanism of action of certain medicinal plants for the treatment of asthma
Ethnopharmacological relevance Asthma is often treated and prevented using the
pharmacological properties of traditional medicinal plants. These healthcare systems are …
pharmacological properties of traditional medicinal plants. These healthcare systems are …
Smoking changes adaptive immunity with persistent effects
Individuals differ widely in their immune responses, with age, sex and genetic factors having
major roles in this inherent variability,,,,–. However, the variables that drive such differences …
major roles in this inherent variability,,,,–. However, the variables that drive such differences …
Single-cell and spatial transcriptome analysis reveals the cellular heterogeneity of liver metastatic colorectal cancer
F Wang, J Long, L Li, ZX Wu, TT Da, XQ Wang… - Science …, 2023 - science.org
In this study, we comprehensively charted the cellular landscape of colorectal cancer (CRC)
and well-matched liver metastatic CRC using single-cell and spatial transcriptome RNA …
and well-matched liver metastatic CRC using single-cell and spatial transcriptome RNA …
Age-induced alterations of granulopoiesis generate atypical neutrophils that aggravate stroke pathology
GS Gullotta, D De Feo, E Friebel, A Semerano… - Nature …, 2023 - nature.com
Aging accounts for increased risk and dismal outcome of ischemic stroke. Here, we
investigated the impact of age-related changes in the immune system on stroke. Upon …
investigated the impact of age-related changes in the immune system on stroke. Upon …
Human umbilical cord mesenchymal stem cell-derived exosomes promote murine skin wound healing by neutrophil and macrophage modulations revealed by single …
Y Liu, M Zhang, Y Liao, H Chen, D Su, Y Tao… - Frontiers in …, 2023 - frontiersin.org
Introduction Full-thickness skin wound healing remains a serious undertaking for patients.
While stem cell-derived exosomes have been proposed as a potential therapeutic approach …
While stem cell-derived exosomes have been proposed as a potential therapeutic approach …
Integrating bulk and single-cell sequencing reveals the phenotype-associated cell subpopulations in sepsis-induced acute lung injury
F Wang, M Chen, J Ma, C Wang, J Wang… - Frontiers in …, 2022 - frontiersin.org
The dysfunctional immune response and multiple organ injury in sepsis is a recurrent theme
impacting prognosis and mortality, while the lung is the first organ invaded by sepsis. To …
impacting prognosis and mortality, while the lung is the first organ invaded by sepsis. To …
Revisiting asthma pharmacotherapy: where do we stand and where do we want to go?
M Cazzola, CP Page, MG Matera… - European …, 2023 - Eur Respiratory Soc
Several current guidelines/strategies outline a treatment approach to asthma, which
primarily consider the goals of improving lung function and quality of life and reducing …
primarily consider the goals of improving lung function and quality of life and reducing …
CXC chemokines in the pathogenesis of pulmonary disease and pharmacological relevance
K Komolafe, M Pacurari - International journal of inflammation, 2022 - Wiley Online Library
Chemokines and their receptors play important roles in the pathophysiology of many
diseases by regulating the cellular migration of major inflammatory and immune players …
diseases by regulating the cellular migration of major inflammatory and immune players …
Abnormal adenosine metabolism of neutrophils inhibits airway inflammation and remodeling in asthma model induced by Aspergillus fumigatus
T Liu, Y Wang, Z Zhang, L Jia, J Zhang, S Zheng… - BMC Pulmonary …, 2023 - Springer
Background Neutrophils consume a large amount of energy when performing their
functions. Compared with other white blood cells, neutrophils contain few mitochondria and …
functions. Compared with other white blood cells, neutrophils contain few mitochondria and …