Ageing and age-related diseases share some basic mechanistic pillars that largely
converge on inflammation. During ageing, chronic, sterile, low-grade inflammation—called …

Inflammatory bowel disease (IBD) and chronic obstructive pulmonary disease (COPD) are
chronic inflammatory diseases of the gastrointestinal and respiratory tracts, respectively …

Low-grade inflammation is a characteristic of the obese state, and adipose tissue releases
many inflammatory mediators. The source of these mediators within adipose tissue is not …

Because of their rare detection in atherosclerotic lesions, the involvement of neutrophils in
the pathophysiology of atherosclerosis has been largely denied. However, over the past …

Background: Bacterial endotoxin is a potently inflammatory antigen that is abundant in the
human gut. Endotoxin circulates at low concentrations in the blood of all healthy individuals …

Background: Meal skipping has become an increasing trend of the modern lifestyle that may
lead to obesity and type 2 diabetes. Objective: We investigated whether the timing of meal …

Raised levels of circulating inflammatory markers are associated with coronary artery
disease, obesity and type II diabetes. It has been proposed that the ingestion of high‐fat …

Obesity is the most prevalent health problem affecting all age groups, and leads to many
complications in the form of chronic heart disease, diabetes mellitus Type 2 and stroke. A …

BACKGROUND: Dietary fat activates systemic innate immune responses, but the effect on
airway responses is unknown. OBJECTIVE: To examine effects of a high-fat versus low-fat …

Impaired glucose tolerance (IGT) serves as a marker for the state of insulin resistance and
predicts both large-and small-vessel vascular complications, independent of a patient's …