When to start and stop bone-protecting medication for preventing glucocorticoid-induced osteoporosis
Glucocorticoid-induced osteoporosis (GIOP) leads to fractures in up to 40% of patients with
chronic glucocorticoid (GC) therapy when left untreated. GCs rapidly increase fracture risk …
chronic glucocorticoid (GC) therapy when left untreated. GCs rapidly increase fracture risk …
Glucocorticoids in rheumatoid arthritis: Balancing benefits and harm by leveraging the therapeutic window of opportunity
M Doumen, S Pazmino, D Bertrand, R Westhovens… - Joint Bone Spine, 2023 - Elsevier
Glucocorticoids have been available since the early 1950s and have since become an
integral part of the management of rheumatoid arthritis (RA). Due to their rapid effect …
integral part of the management of rheumatoid arthritis (RA). Due to their rapid effect …
Bone Loss in Inflammatory Rheumatic Musculoskeletal Disease Patients Treated With Low‐Dose Glucocorticoids and Prevention by Anti‐Osteoporosis Medications
Objective The negative effects of glucocorticoids on bone depend on dose and treatment
duration. However, it is unclear whether a safe dose exists, especially for patients with …
duration. However, it is unclear whether a safe dose exists, especially for patients with …
Biological disease-modifying antirheumatic drugs and osteoporotic fracture risk in patients with rheumatoid arthritis: a Danish cohort study
Objectives Clinical trials have shown a beneficial effect from biological disease-modifying
antirheumatic drugs (bDMARDs) on hand or axial bone loss in patients with rheumatoid …
antirheumatic drugs (bDMARDs) on hand or axial bone loss in patients with rheumatoid …
Damaged bone microarchitecture by Trabecular Bone Score (TBS) and low appendicular muscle mass: main risk factors for vertebral and non-vertebral fractures in …
FF Silva, GR Machado, ACM Ribeiro… - Osteoporosis …, 2024 - Springer
We ascertained the fracture risk factors stratified by vertebral and non-vertebral sites in
rheumatoid arthritis (RA) females. Bone/muscle features, but not disease activity, were the …
rheumatoid arthritis (RA) females. Bone/muscle features, but not disease activity, were the …
High incidence of clinical fragility fractures in postmenopausal women with rheumatoid arthritis. A case-control study
C Gómez-Vaquero, JL Hernández, JM Olmos, D Cerdà… - Bone, 2023 - Elsevier
Objectives To estimate the incidence of clinical fragility fractures in postmenopausal women
with rheumatoid arthritis (RA) and analyze risk factors for fracture. Methods Incidence of …
with rheumatoid arthritis (RA) and analyze risk factors for fracture. Methods Incidence of …
Systematic review for the treatment of older rheumatoid arthritis patients informing the 2020 update of the Japan College of Rheumatology clinical practice guidelines …
T Sugihara, Y Kawahito, A Morinobu… - Modern …, 2022 - academic.oup.com
Objectives To provide an evidence base for clinical practice guidelines (CPG) for the
management of rheumatoid arthritis (RA) in older adults. Methods PubMed, Cochrane …
management of rheumatoid arthritis (RA) in older adults. Methods PubMed, Cochrane …
Osteoporosis and fracture risk are multifactorial in patients with inflammatory rheumatic diseases
Patients with inflammatory rheumatic and musculoskeletal diseases (iRMDs) such as
rheumatoid arthritis, connective tissue diseases, vasculitides and spondyloarthropathies are …
rheumatoid arthritis, connective tissue diseases, vasculitides and spondyloarthropathies are …
The safety of glucocorticoids in the treatment of inflammatory rheumatic disease: new evidence
M Luís, M Boers, K Saag, F Buttgereit… - Current Opinion in …, 2022 - journals.lww.com
Based on current evidence the benefit–risk balance of low-dose glucocorticoids in
rheumatoid arthritis, and probably in other rheumatic diseases is generally favourable …
rheumatoid arthritis, and probably in other rheumatic diseases is generally favourable …
Personalized therapeutic strategies in the management of osteoporosis in patients with autoantibody-positive rheumatoid arthritis
B D'Onofrio, M di Lernia, L De Stefano… - Journal of Clinical …, 2022 - mdpi.com
Bone mineral density (BMD) reduction and fragility fractures still represent a major source of
morbidity in rheumatoid arthritis (RA) patients, despite adequate control of the disease. An …
morbidity in rheumatoid arthritis (RA) patients, despite adequate control of the disease. An …