An understanding of the diversity of cortical GABAergic interneurons is critical to understand
the function of the cerebral cortex. Recent data suggest that neurons expressing three …

Through a widespread efferent projection system, the locus coeruleus–noradrenergic
system supplies norepinephrine throughout the central nervous system. Initial studies …

We present a first-draft digital reconstruction of the microcircuitry of somatosensory cortex of
juvenile rat. The reconstruction uses cellular and synaptic organizing principles to …

The output of cortical columns is routed to different downstream targets via distinct pathways:
cortico-cortical and cortico-subcortical. It is as yet unclear what roles these pathways play in …

What happens in our brain when we make a decision? What triggers a neuron to send out a
signal? What is the neural code? This textbook for advanced undergraduate and beginning …

Abstract The Hodgkin–Huxley model for action potential generation in biological axons is
central for understanding the computational capability of the nervous system and emulating …

Despite the importance of the mammalian neocortex for complex cognitive processes, we
still lack a comprehensive description of its cellular components. To improve the …

Though mathematical ideas underpin the study of neural networks, the author presents the
fundamentals without the full mathematical apparatus. All aspects of the field are tackled …

A model is presented that reproduces spiking and bursting behavior of known types of
cortical neurons. The model combines the biologically plausibility of Hodgkin-Huxley-type …

Neurons in the brain communicate by short electrical pulses, the so-called action potentials
or spikes. How can we understand the process of spike generation? How can we …