miRNAs as cornerstones in colorectal cancer pathogenesis and resistance to therapy: A spotlight on signaling pathways interplay—A review

MA Elrebehy, S Al-Saeed, S Gamal, A El-Sayed… - International journal of …, 2022 - Elsevier
Colorectal cancer (CRC) is the world's third most prevalent cancer and the main cause of
cancer-related mortality. A lot of work has been put into improving CRC patients' clinical …

MicroRNAs and complex diseases: from experimental results to computational models

X Chen, D Xie, Q Zhao, ZH You - Briefings in bioinformatics, 2019 - academic.oup.com
Plenty of microRNAs (miRNAs) were discovered at a rapid pace in plants, green algae,
viruses and animals. As one of the most important components in the cell, miRNAs play a …

An estimate of the total number of true human miRNAs

J Alles, T Fehlmann, U Fischer, C Backes… - Nucleic acids …, 2019 - academic.oup.com
While the number of human miRNA candidates continuously increases, only a few of them
are completely characterized and experimentally validated. Toward determining the total …

MicroRNA and cancer–a brief overview

M Acunzo, G Romano, D Wernicke… - Advances in biological …, 2015 - Elsevier
MicroRNAs (miRNAs) are short non-coding RNAs with a length of∼ 22 nucleotides,
involved in posttranscriptional regulation of gene expression. Until now, over 2588 miRNAs …

WBSMDA: within and between score for MiRNA-disease association prediction

X Chen, CC Yan, X Zhang, ZH You, L Deng, Y Liu… - Scientific reports, 2016 - nature.com
Increasing evidences have indicated that microRNAs (miRNAs) are functionally associated
with the development and progression of various complex human diseases. However, the …

EGBMMDA: extreme gradient boosting machine for MiRNA-disease association prediction

X Chen, L Huang, D Xie, Q Zhao - Cell death & disease, 2018 - nature.com
Associations between microRNAs (miRNAs) and human diseases have been identified by
increasing studies and discovering new ones is an ongoing process in medical laboratories …

[HTML][HTML] MicroRNAs in the prognosis and therapy of colorectal cancer: From bench to bedside

KKW To, CWS Tong, M Wu… - World journal of …, 2018 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are small, single-stranded, noncoding RNAs that can post-
transcriptionally regulate the expression of various oncogenes and tumor suppressor genes …

[HTML][HTML] HGIMDA: Heterogeneous graph inference for miRNA-disease association prediction

X Chen, CC Yan, X Zhang, ZH You, YA Huang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Recently, microRNAs (miRNAs) have drawn more and more attentions because
accumulating experimental studies have indicated miRNA could play critical roles in multiple …

From strings to signals: Unraveling the impact of miRNAs on diagnosis, and progression of colorectal cancer

OA Mohammed - Pathology-Research and Practice, 2023 - Elsevier
Colorectal cancer (CRC) stands as the third most prevalent ailment globally and represents
the primary cause of mortality associated with cancer. Significant advancements have been …

MiR-770 suppresses the chemo-resistance and metastasis of triple negative breast cancer via direct targeting of STMN1

Y Li, Y Liang, Y Sang, X Song, H Zhang, Y Liu… - Cell death & …, 2018 - nature.com
Chemo-resistance and metastasis of triple negative breast cancer (TNBC) contributed the
most of treatment failure in the clinic. MicroRNAs (miRNAs) have been proved to be involved …