Background The prevalence of gastroesophageal reflux disease (GERD) has increased in
the last decades and it is now one of the most common chronic diseases. Throughout time …

The gastrointestinal mucosal barrier plays an essential role in the separation of the inside of
the body from the outside environment. Tight junctions (TJs) are the most important …

The desmosomal cadherin desmoglein-1 (DSG1) is an essential intercellular adhesion
molecule that is altered in various human cutaneous disorders; however, its regulation and …

Background Despite gastro‐esophageal reflux disease affecting up to 20% of Western
populations, relatively little is known about the molecular mechanisms underlying its most …

Background & Aims Mucosal integrity can be assessed in patients with gastroesophageal
reflux disease (GERD) by measuring intraluminal baseline impedance (BI). However, it is …

Brachycephalic obstructive airway syndrome (BOAS) is a chronic, lifelong, debilitating,
primarily obstructive airway disease which adversely affects the quality of life of many …

There is increasing concern in identifying the mechanisms underlying the intimate control of
the intestinal barrier, as deregulation of its function is strongly associated with digestive …

Increased esophageal sensitivity and impaired mucosal integrity have both been described
in patients with gastroesophageal reflux disease, but the relationship between …

Campylobacter jejuni express the high temperature requirement protein A (HtrA), a secreted
serine protease, which is implicated in virulence properties of the pathogen. Previous …

Гастроэзофагеальная рефлюксная болезнь (ГЭРБ) характеризуется высокой
заболеваемостью и значительным снижением качества жизни пациентов, а также …