Introduction Identification of therapeutic targets in head and neck squamous cell carcinoma
(HNSCC) is essential because most of the patients with advanced HNSCC have a poor …

Urinary bladder cancer is a common malignancy in industrialized countries. More than 90%
of bladder cancer originates in the transitional cells. Bladder transitional cancer prognosis is …

Hox genes (HOX in humans), an evolutionary preserved gene family, are key determinants
of embryonic development and cell memory gene program. Hox genes are organized in four …

Human bone marrow-derived mesenchymal stem cells (hMSCs) have been shown to
possess multilineage differentiation potential. HOX genes function in transcriptional …

Homeobox C6 (HOXC6) genes belong to the homeoprotein family of transcription factors,
which play an important role in morphogenesis and cellular differentiation during embryonic …

HOXB13 is a homeobox protein that is expressed in normal adult prostate and colon tissues;
however, its deregulated expression was evidenced in various malignancies. To …

Human HOX genes encode transcription factors that act as master regulators of embryonic
development. They are important in several processes such as cellular morphogenesis and …

Background: Hox genes belong to a highly conserved subgroup of the homeobox gene
superfamily. Studies of animal models have emphasized their role in defining the body plan …

Introduction The role of HOXB13 in bladder and renal tumorigenesis is unclear. Our goal
was to determine the prevalence of HOXB13 p. G84E mutation in bladder and kidney cancer …