Metformin is the most commonly used treatment to increase insulin sensitivity in insulin-
resistant (IR) conditions such as diabetes, prediabetes, polycystic ovary syndrome, and …

The SLC2 genes code for a family of GLUT proteins that are part of the major facilitator
superfamily (MFS) of membrane transporters. Crystal structures have recently revealed how …

It is the purpose of this viewpoint article to delineate the regulatory network of growth
hormone (GH), insulin, and insulin‐like growth factor‐1 (IGF‐1) signalling during puberty …

Insulin resistance is a major risk factor for developing type 2 diabetes caused by the inability
of insulin-target tissues to respond properly to insulin, and contributes to the morbidity of …

There is extensive experimental evidence that sex steroids and insulin interact in their
actions on tissues. At physiological levels, testosterone and oestradiol are thought to be …

Evidence suggests that chromium supplementation may alleviate symptoms associated with
diabetes, such as high blood glucose and lipid abnormalities, yet a molecular mechanism …

Metformin lowers blood glucose levels in type 2 diabetic patients. To evaluate the insulin
sensitizing action of metformin on skeletal muscle cells, we have used C2C12 skeletal …

Insulin resistance is a pathophysiological link of obesity to type 2 diabetes. The initial cause
of insulin resistance is critical for prevention and treatment of type 2 diabetes. Lipotoxicity is …

The association between acne and insulin resistance has not been investigated as
thoroughly in males as it has been in women, despite the fact that in adult men, acne …

Insulin resistance, the hallmark of type 2 diabetes mellitus (T2DM), is linked to
hyperinsulinemia, which develops to counterbalance initial peripheral hormone resistance …