Insights and implications of sexual dimorphism in osteoporosis

YY Zhang, N Xie, XD Sun, EC Nice, YC Liou, C Huang… - Bone research, 2024 - nature.com
Osteoporosis, a metabolic bone disease characterized by low bone mineral density and
deterioration of bone microarchitecture, has led to a high risk of fatal osteoporotic fractures …

Vitamin D metabolites in captivity? Should we measure free or total 25 (OH) D to assess vitamin D status?

D Bikle, R Bouillon, R Thadhani… - The Journal of steroid …, 2017 - Elsevier
There is general consensus that serum 25 (OH) D is the best biochemical marker for
nutritional vitamin D status. Whether free 25 (OH) D would be a better marker than total 25 …

Vitamin D–binding protein modifies the vitamin D–bone mineral density relationship

CE Powe, C Ricciardi, AH Berg… - Journal of Bone and …, 2011 - academic.oup.com
Studies examining the relationship between total circulating 25‐hydroxyvitamin D [25 (OH)
D] levels and bone mineral density (BMD) have yielded mixed results. Vitamin D–binding …

[HTML][HTML] Genetic polymorphisms of the vitamin D binding protein and plasma concentrations of 25-hydroxyvitamin D in premenopausal women

M Sinotte, C Diorio, S Bérubé, M Pollak… - The American journal of …, 2009 - Elsevier
Background: Vitamin D status, determined on the basis of 25-hydroxyvitamin D [25 (OH) D]
concentrations, is associated with the risk of several diseases. Vitamin D binding protein …

Common variants of the vitamin D binding protein gene and adverse health outcomes

S Malik, L Fu, DJ Juras, M Karmali… - Critical reviews in …, 2013 - Taylor & Francis
The vitamin D binding protein (DBP) is the major plasma carrier for vitamin D and its
metabolites, but it is also an actin scavenger, and is the precursor to the immunomodulatory …

Genetics of osteoporosis: accelerating pace in gene identification and validation

WF Li, SX Hou, B Yu, MM Li, C Férec, JM Chen - Human genetics, 2010 - Springer
Osteoporosis is characterized by low bone mineral density and structural deterioration of
bone tissue, leading to an increased risk of fractures. It is the most common metabolic bone …

Insights into the role of circadian rhythms in bone metabolism: a promising intervention target?

C Song, J Wang, B Kim, C Lu, Z Zhang… - BioMed research …, 2018 - Wiley Online Library
Numerous physiological processes of mammals, including bone metabolism, are regulated
by the circadian clock system, which consists of a central regulator, the suprachiasmatic …

Vitamin d binding protein and bone health

I Bhan - International journal of endocrinology, 2014 - Wiley Online Library
Vitamin D binding protein (DBP) is the major carrier protein of 25‐hydroxyvitamin D (25 (OH)
D) in the circulation, where it may serve roles in maintaining stable levels during times of …

An update of the effects of vitamins D and C in critical illness

A Hill, C Starchl, E Dresen, C Stoppe… - Frontiers in Medicine, 2023 - frontiersin.org
Many critically ill patients are vitamin D and vitamin C deficient and the current international
guidelines state that hypovitaminoses should be compensated. However, uncertainty about …

Vitamin D, muscle and bone: Integrating effects in development, aging and injury

CM Girgis, PA Baldock, M Downes - Molecular and cellular endocrinology, 2015 - Elsevier
Beyond the established effects of muscle loading on bone, a complex network of hormones
and growth factors integrates these adjacent tissues. One such hormone, vitamin D, exerts …