Insights and implications of sexual dimorphism in osteoporosis
Osteoporosis, a metabolic bone disease characterized by low bone mineral density and
deterioration of bone microarchitecture, has led to a high risk of fatal osteoporotic fractures …
deterioration of bone microarchitecture, has led to a high risk of fatal osteoporotic fractures …
Vitamin D metabolites in captivity? Should we measure free or total 25 (OH) D to assess vitamin D status?
D Bikle, R Bouillon, R Thadhani… - The Journal of steroid …, 2017 - Elsevier
There is general consensus that serum 25 (OH) D is the best biochemical marker for
nutritional vitamin D status. Whether free 25 (OH) D would be a better marker than total 25 …
nutritional vitamin D status. Whether free 25 (OH) D would be a better marker than total 25 …
Vitamin D–binding protein modifies the vitamin D–bone mineral density relationship
Studies examining the relationship between total circulating 25‐hydroxyvitamin D [25 (OH)
D] levels and bone mineral density (BMD) have yielded mixed results. Vitamin D–binding …
D] levels and bone mineral density (BMD) have yielded mixed results. Vitamin D–binding …
[HTML][HTML] Genetic polymorphisms of the vitamin D binding protein and plasma concentrations of 25-hydroxyvitamin D in premenopausal women
M Sinotte, C Diorio, S Bérubé, M Pollak… - The American journal of …, 2009 - Elsevier
Background: Vitamin D status, determined on the basis of 25-hydroxyvitamin D [25 (OH) D]
concentrations, is associated with the risk of several diseases. Vitamin D binding protein …
concentrations, is associated with the risk of several diseases. Vitamin D binding protein …
Common variants of the vitamin D binding protein gene and adverse health outcomes
The vitamin D binding protein (DBP) is the major plasma carrier for vitamin D and its
metabolites, but it is also an actin scavenger, and is the precursor to the immunomodulatory …
metabolites, but it is also an actin scavenger, and is the precursor to the immunomodulatory …
Genetics of osteoporosis: accelerating pace in gene identification and validation
Osteoporosis is characterized by low bone mineral density and structural deterioration of
bone tissue, leading to an increased risk of fractures. It is the most common metabolic bone …
bone tissue, leading to an increased risk of fractures. It is the most common metabolic bone …
Insights into the role of circadian rhythms in bone metabolism: a promising intervention target?
Numerous physiological processes of mammals, including bone metabolism, are regulated
by the circadian clock system, which consists of a central regulator, the suprachiasmatic …
by the circadian clock system, which consists of a central regulator, the suprachiasmatic …
Vitamin d binding protein and bone health
I Bhan - International journal of endocrinology, 2014 - Wiley Online Library
Vitamin D binding protein (DBP) is the major carrier protein of 25‐hydroxyvitamin D (25 (OH)
D) in the circulation, where it may serve roles in maintaining stable levels during times of …
D) in the circulation, where it may serve roles in maintaining stable levels during times of …
An update of the effects of vitamins D and C in critical illness
Many critically ill patients are vitamin D and vitamin C deficient and the current international
guidelines state that hypovitaminoses should be compensated. However, uncertainty about …
guidelines state that hypovitaminoses should be compensated. However, uncertainty about …
Vitamin D, muscle and bone: Integrating effects in development, aging and injury
Beyond the established effects of muscle loading on bone, a complex network of hormones
and growth factors integrates these adjacent tissues. One such hormone, vitamin D, exerts …
and growth factors integrates these adjacent tissues. One such hormone, vitamin D, exerts …