The role of mitochondria in mood disorders: from physiology to pathophysiology and to treatment

A Giménez-Palomo, S Dodd, G Anmella… - Frontiers in …, 2021 - frontiersin.org
Mitochondria are cellular organelles involved in several biological processes, especially in
energy production. Several studies have found a relationship between mitochondrial …

[HTML][HTML] Associations between depression and cognition, mild cognitive impairment and dementia in persons with diabetes mellitus: A systematic review and meta …

YY Chow, M Verdonschot, CT McEvoy… - Diabetes research and …, 2022 - Elsevier
Aims This systematic review aimed to examine whether persons with diabetes and
depression had poorer cognition and higher dementia risk than persons with diabetes only …

Depression and suicide risk screening: updated evidence report and systematic review for the US preventive services task force

EA O'Connor, LA Perdue, EL Coppola, ML Henninger… - JAMA, 2023 - jamanetwork.com
Importance Depression is common and associated with substantial burden. Suicide rates
have increased over the past decade, and both suicide attempts and deaths have …

Pharmacotherapy of behavioral and psychological symptoms of dementia: state of the art and future progress

R Magierski, T Sobow, E Schwertner… - Frontiers in …, 2020 - frontiersin.org
The core symptoms of different dementia subtypes are the behavioral and psychological
symptoms of dementia (BPSD) and its neuropsychiatric symptoms (NPS). BPSD symptoms …

Association of antidepressant use with adverse health outcomes: a systematic umbrella review

E Dragioti, M Solmi, A Favaro, P Fusar-Poli… - JAMA …, 2019 - jamanetwork.com
Importance Antidepressant use is increasing worldwide. Yet, contrasting evidence on the
safety of antidepressants is available from meta-analyses, and the credibility of these …

Understanding neuropsychiatric symptoms in Alzheimer's disease: challenges and advances in diagnosis and treatment

A Pless, D Ware, S Saggu, H Rehman… - Frontiers in …, 2023 - frontiersin.org
Neuropsychiatric symptoms (NPS) in Alzheimer's disease (AD) affect up to 97% of AD
patients, with an estimated 80% of current AD patients experiencing these symptoms …

Association between use of statin and risk of dementia: a meta-analysis of observational studies

TN Poly, MM Islam, BA Walther, HC Yang, CC Wu… - …, 2020 - karger.com
Abstract Background and Aims: The impact of statin on dementia risk reduction has been a
subject of debate over the last decade, but the evidence remains inconclusive. Therefore …

Molecular signatures of premature aging in Major Depression and Substance Use Disorders

A Onisiforou, P Zanos, P Georgiou - Scientific Data, 2024 - nature.com
Major depressive disorder (MDD) and substance-use disorders (SUDs) often lead to
premature aging, increasing vulnerability to cognitive decline and other forms of dementia …

Association between atrial fibrillation and dementia: a meta-analysis

MM Islam, TN Poly, BA Walther, HC Yang… - Frontiers in aging …, 2019 - frontiersin.org
Background: A potential evidence from previous epidemiological studies remains conflicting
findings regarding the association between atrial fibrillation (AF) and dementia risk. We …

Anxiety and Alzheimer's disease pathogenesis: focus on 5-HT and CRF systems in 3xTg-AD and TgF344-AD animal models

NC Reyna, BJ Clark, DA Hamilton… - Frontiers in Aging …, 2023 - frontiersin.org
Dementia remains one of the leading causes of morbidity and mortality in older adults.
Alzheimer's disease (AD) is the most common type of dementia, affecting over 55 million …