Iron homeostasis disorder and Alzheimer's disease

Y Peng, X Chang, M Lang - International journal of molecular sciences, 2021 - mdpi.com
Iron is an essential trace metal for almost all organisms, including human; however,
oxidative stress can easily be caused when iron is in excess, producing toxicity to the human …

Iron metabolism, ferroptosis, and the links with Alzheimer's disease

N Yan, JJ Zhang - Frontiers in neuroscience, 2020 - frontiersin.org
Iron is an essential transition metal for numerous biologic processes in mammals. Iron
metabolism is regulated via several coordination mechanisms including absorption …

[HTML][HTML] Role and mechanism of ferroptosis in neurological diseases

M Ou, Y Jiang, Y Ji, Q Zhou, Z Du, H Zhu, Z Zhou - Molecular Metabolism, 2022 - Elsevier
Background Ferroptosis, as a new form of cell death, is different from other cell deaths such
as autophagy or senescence. Ferroptosis involves in the pathophysiological progress of …

Transgenic mouse models of Alzheimer's disease: An integrative analysis

R Sanchez-Varo, M Mejias-Ortega… - International Journal of …, 2022 - mdpi.com
Alzheimer's disease (AD) constitutes the most prominent form of dementia among elderly
individuals worldwide. Disease modeling using murine transgenic mice was first initiated …

Natural compounds and autophagy: allies against neurodegeneration

A Stacchiotti, G Corsetti - Frontiers in cell and developmental biology, 2020 - frontiersin.org
Prolonging the healthy life span and limiting neurological illness are imperative goals in
gerontology. Age-related neurodegeneration is progressive and leads to severe diseases …

Primary hypothyroidism and Alzheimer's Disease: a tale of two

FH AlAnazi, HM Al-Kuraishy, A Alexiou… - Cellular and Molecular …, 2023 - Springer
Hypothyroidism (HPT) HPT could be a risk factor for the development and progression of
Alzheimer's disease (AD). In addition, progressive neurodegeneration in AD may affect the …

Cerebrospinal fluid: A specific biofluid for the biosensing of Alzheimer's diseases biomarkers

A Mirzaie, H Nasrollahpour, B Khalilzadeh… - TrAC Trends in …, 2023 - Elsevier
Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder with an
irreversible, progressive, and untreatable nature that causes progressive deterioration, loss …

Marine sources of DHA-rich phospholipids with anti-Alzheimer effect

I Ferreira, AP Rauter, NM Bandarra - Marine Drugs, 2022 - mdpi.com
Alzheimer's disease (AD) is a complex and progressive disease, which affects millions of
people around the world. Despite the many efforts over the years to find efficient …

The Antioxidant Activity of Limonene Counteracts Neurotoxicity Triggered byAβ1-42 Oligomers in Primary Cortical Neurons

I Piccialli, V Tedeschi, L Caputo, G Amato, L De Martino… - Antioxidants, 2021 - mdpi.com
Many natural-derived compounds, including the essential oils from plants, are investigated
to find new potential protective agents in several neurodegenerative disorders such as …

Therapeutic potential of natural compounds in neurodegenerative diseases: insights from clinical trials

S Andrade, D Nunes, M Dabur, MJ Ramalho… - Pharmaceutics, 2023 - mdpi.com
Neurodegenerative diseases are caused by the gradual loss of neurons' function. These
neurological illnesses remain incurable, and current medicines only alleviate the symptoms …