Medicinal plants in Brazil: Pharmacological studies, drug discovery, challenges and perspectives

RC Dutra, MM Campos, ARS Santos… - Pharmacological research, 2016 - Elsevier
This review article focuses on pre-clinical and clinical studies with some selected Brazilian
medicinal plants in different areas of interest, conducted by research groups in Brazil and …

Metabolites from marine microorganisms, micro, and macroalgae: Immense scope for pharmacology

N Barzkar, ST Jahromi, HB Poorsaheli, F Vianello - Marine drugs, 2019 - mdpi.com
Marine organisms produce a large array of natural products with relevance in drug
discovery. These compounds have biological activities such as antioxidant, antibacterial …

[HTML][HTML] New drugs with antiprotozoal activity from marine algae: a review

FAE Torres, TG Passalacqua, A Velásquez… - Revista Brasileira de …, 2014 - SciELO Brasil
The use of indigenous or remote popular knowledge to identify new drugs against diseases
or infections is a well-known approach in medicine. The inhabitants of coastal regions are …

Antifungal activity and preliminary mechanism of pristimerin against Sclerotinia sclerotiorum

WB Zhao, ZM Zhao, Y Ma, AP Li, ZJ Zhang… - Industrial Crops and …, 2022 - Elsevier
Abstract Sclerotinia sclerotiorum (Lib.) de Bary is a crop-threatening fungus. Natural
products are ideal antimicrobial agents to combat pathogens. They are considered a …

The potential of secondary metabolites from plants as drugs or leads against trypanosoma cruzi-an update from 2012 to 2021

H Barbosa, F Thevenard… - Current Topics in …, 2023 - ingentaconnect.com
Background: Chagas disease (American Trypanosomiasis) is classified by the World Health
Organization (WHO) as one of the seventeen neglected tropical diseases (NTD), affecting …

A sample-centric and knowledge-driven computational framework for natural products drug discovery

A Gaudry, M Pagni, F Mehl, S Moretti… - 2024 - ACS Publications
A Sample-Centric and Knowledge-Driven Computational Framework for Natural Products Drug
Discovery | ACS Central Science ACS ACS Publications C&EN CAS Find my institution Log In …

Antimicrobial activity of RP-1 peptide conjugate with ferrocene group

NCS Costa, JP Piccoli, NA Santos-Filho… - Plos one, 2020 - journals.plos.org
Parasitic diseases are a neglected and serious problem, especially in underdeveloped
countries. Among the major parasitic diseases, Leishmaniasis figures as an urgent …

Pentacyclic Triterpenoids Isolated from Celastraceae: A Focus in the 13C-NMR Data

KC Camargo, MG de Aguilar, ARA Moraes… - Molecules, 2022 - mdpi.com
The Celastraceae family comprises about 96 genera and more than 1.350 species,
occurring mainly in tropical and subtropical regions of the world. The species of this family …

Leishmanicidal activities of novel synthetic furoxan and benzofuroxan derivatives

LA Dutra, L de Almeida, TG Passalacqua… - Antimicrobial Agents …, 2014 - Am Soc Microbiol
ABSTRACT A novel series of furoxan (1, 2, 5-oxadiazole 2-oxide)(compounds 3, 4a and-b,
13a and-b, and 14a to-f) and benzofuroxan (benzo [c][1, 2, 5] oxadiazole 1 …

Nanotechnological strategies for treatment of leishmaniasis—a review

L De Almeida, AT Fujimura, MLD Cistia… - Journal of …, 2017 - ingentaconnect.com
The World Health Organization (WHO) estimates that more than one billion people suffer
from neglected tropical diseases. Leishmaniasis is a widespread disease, affecting 12 …