The testis must create and maintain an immune privileged environment to protect maturing
germ cells from autoimmune destruction. The establishment of this protective environment is …

The production, differentiation, and presence of male gametes represent inimitable
challenges to the immune system, as they are unique to the body and appear long after the …

Inflammatory mechanisms are believed to play an important role in hyperalgesia resulting
from nerve injury. Hyperalgesia following nerve injury is temporally linked with Wallerian …

The Sertoli cells are critical regulators of testis differentiation and development. In the adult,
however, their known function is restricted largely to maintenance of spermatogenesis. To …

Immune responses within the testis are regulated in a manner that provides protection for
the developing male germ cells, while permitting qualitatively normal inflammatory …

Macrophages are found throughout reproductive tissues. To determine their role (s), we
have studied mice homozygous for a null mutation (Csfmop) in the gene encoding the major …

Programmed cell death is an evolutionarily conserved cell death process that plays a major
role during normal development and homeostasis. In many cases, the ordered execution of …

The perivascular (PVM) and meningeal (MM) macrophages form a distinct population of
resident CNS cells, selectively expressing the mature macrophage marker ED2 in the rat. In …

The purpose of this minireview is to present information concerning the morphologic and
functional relationship between testicular macrophages and Leydig cells. Although data …

The soy phytoestrogen, genistein, induces thymic atrophy when administered to
ovariectomized mice by injection or in the diet. Injected genistein also causes decreased …