Circularly polarized luminescence in nanoassemblies: generation, amplification, and application
Currently, the development of circularly polarized luminescent (CPL) materials has drawn
extensive attention due to the numerous potential applications in optical data storage …
extensive attention due to the numerous potential applications in optical data storage …
Imaging neurotransmitter and neuromodulator dynamics in vivo with genetically encoded indicators
BL Sabatini, L Tian - Neuron, 2020 - cell.com
The actions of neuromodulation are thought to mediate the ability of the mammalian brain to
dynamically adjust its functional state in response to changes in the environment. Altered …
dynamically adjust its functional state in response to changes in the environment. Altered …
A guide to fluorescent protein FRET pairs
Förster or fluorescence resonance energy transfer (FRET) technology and genetically
encoded FRET biosensors provide a powerful tool for visualizing signaling molecules in live …
encoded FRET biosensors provide a powerful tool for visualizing signaling molecules in live …
Repurposing an adenine riboswitch into a fluorogenic imaging and sensing tag
Fluorogenic RNA aptamers are used to genetically encode fluorescent RNA and to construct
RNA-based metabolite sensors. Unlike naturally occurring aptamers that efficiently fold and …
RNA-based metabolite sensors. Unlike naturally occurring aptamers that efficiently fold and …
Fluorescent biosensors for neurotransmission and neuromodulation: engineering and applications
AV Leopold, DM Shcherbakova… - Frontiers in cellular …, 2019 - frontiersin.org
Understanding how neuronal activity patterns in the brain correlate with complex behavior is
one of the primary goals of modern neuroscience. Chemical transmission is the major way of …
one of the primary goals of modern neuroscience. Chemical transmission is the major way of …
Imaging metabolite dynamics in living cells using a Spinach-based riboswitch
Riboswitches are natural ligand-sensing RNAs typically that are found in the 5′ UTRs of
mRNA. Numerous classes of riboswitches have been discovered, enabling mRNA to be …
mRNA. Numerous classes of riboswitches have been discovered, enabling mRNA to be …
Circularly permuted fluorescent protein-based indicators: history, principles, and classification
AI Kostyuk, AD Demidovich, DA Kotova… - International journal of …, 2019 - mdpi.com
Genetically encoded biosensors based on fluorescent proteins (FPs) are a reliable tool for
studying the various biological processes in living systems. The circular permutation of …
studying the various biological processes in living systems. The circular permutation of …
Genetically encoded fluorescent indicators for imaging intracellular potassium ion concentration
Potassium ion (K+) homeostasis and dynamics play critical roles in biological activities. Here
we describe three genetically encoded K+ indicators. KIRIN1 (potassium (K) i on r atiometric …
we describe three genetically encoded K+ indicators. KIRIN1 (potassium (K) i on r atiometric …
Development of a genetically encodable FRET system using fluorescent RNA aptamers
MDE Jepsen, SM Sparvath, TB Nielsen… - Nature …, 2018 - nature.com
Fluorescent RNA aptamers are useful as markers for tracking RNA molecules inside cells
and for creating biosensor devices. Förster resonance energy transfer (FRET) based on …
and for creating biosensor devices. Förster resonance energy transfer (FRET) based on …
Repurposing conformational changes in ANL superfamily enzymes to rapidly generate biosensors for organic and amino acids
J Wang, N Xue, W Pan, R Tu, S Li, Y Zhang… - Nature …, 2023 - nature.com
Biosensors are powerful tools for detecting, real-time imaging, and quantifying molecules,
but rapidly constructing diverse genetically encoded biosensors remains challenging. Here …
but rapidly constructing diverse genetically encoded biosensors remains challenging. Here …