Circularly polarized luminescence in nanoassemblies: generation, amplification, and application

Y Sang, J Han, T Zhao, P Duan, M Liu - Advanced Materials, 2020 - Wiley Online Library
Currently, the development of circularly polarized luminescent (CPL) materials has drawn
extensive attention due to the numerous potential applications in optical data storage …

Imaging neurotransmitter and neuromodulator dynamics in vivo with genetically encoded indicators

BL Sabatini, L Tian - Neuron, 2020 - cell.com
The actions of neuromodulation are thought to mediate the ability of the mammalian brain to
dynamically adjust its functional state in response to changes in the environment. Altered …

A guide to fluorescent protein FRET pairs

BT Bajar, ES Wang, S Zhang, MZ Lin, J Chu - Sensors, 2016 - mdpi.com
Förster or fluorescence resonance energy transfer (FRET) technology and genetically
encoded FRET biosensors provide a powerful tool for visualizing signaling molecules in live …

Repurposing an adenine riboswitch into a fluorogenic imaging and sensing tag

SK Dey, GS Filonov, AO Olarerin-George… - Nature chemical …, 2022 - nature.com
Fluorogenic RNA aptamers are used to genetically encode fluorescent RNA and to construct
RNA-based metabolite sensors. Unlike naturally occurring aptamers that efficiently fold and …

Fluorescent biosensors for neurotransmission and neuromodulation: engineering and applications

AV Leopold, DM Shcherbakova… - Frontiers in cellular …, 2019 - frontiersin.org
Understanding how neuronal activity patterns in the brain correlate with complex behavior is
one of the primary goals of modern neuroscience. Chemical transmission is the major way of …

Imaging metabolite dynamics in living cells using a Spinach-based riboswitch

M You, JL Litke, SR Jaffrey - Proceedings of the National …, 2015 - National Acad Sciences
Riboswitches are natural ligand-sensing RNAs typically that are found in the 5′ UTRs of
mRNA. Numerous classes of riboswitches have been discovered, enabling mRNA to be …

Circularly permuted fluorescent protein-based indicators: history, principles, and classification

AI Kostyuk, AD Demidovich, DA Kotova… - International journal of …, 2019 - mdpi.com
Genetically encoded biosensors based on fluorescent proteins (FPs) are a reliable tool for
studying the various biological processes in living systems. The circular permutation of …

Genetically encoded fluorescent indicators for imaging intracellular potassium ion concentration

Y Shen, SY Wu, V Rancic, A Aggarwal, Y Qian… - Communications …, 2019 - nature.com
Potassium ion (K+) homeostasis and dynamics play critical roles in biological activities. Here
we describe three genetically encoded K+ indicators. KIRIN1 (potassium (K) i on r atiometric …

Development of a genetically encodable FRET system using fluorescent RNA aptamers

MDE Jepsen, SM Sparvath, TB Nielsen… - Nature …, 2018 - nature.com
Fluorescent RNA aptamers are useful as markers for tracking RNA molecules inside cells
and for creating biosensor devices. Förster resonance energy transfer (FRET) based on …

Repurposing conformational changes in ANL superfamily enzymes to rapidly generate biosensors for organic and amino acids

J Wang, N Xue, W Pan, R Tu, S Li, Y Zhang… - Nature …, 2023 - nature.com
Biosensors are powerful tools for detecting, real-time imaging, and quantifying molecules,
but rapidly constructing diverse genetically encoded biosensors remains challenging. Here …