Amplification-free CRISPR/Cas detection technology: challenges, strategies, and perspectives

H Li, Y Xie, F Chen, H Bai, L Xiu, X Zhou… - Chemical Society …, 2023 - pubs.rsc.org
Rapid and accurate molecular diagnosis is a prerequisite for precision medicine, food
safety, and environmental monitoring. The clustered regularly interspaced short palindromic …

Visible-light and near-infrared fluorescence and surface-enhanced Raman scattering point-of-care sensing and bio-imaging: A review

Y Hang, J Boryczka, N Wu - Chemical Society Reviews, 2022 - pubs.rsc.org
This review article deals with the concepts, principles and applications of visible-light and
near-infrared (NIR) fluorescence and surface-enhanced Raman scattering (SERS) in in vitro …

CRISPR/Cas systems towards next-generation biosensing

Y Li, S Li, J Wang, G Liu - Trends in biotechnology, 2019 - cell.com
Beyond its remarkable genome editing ability, the CRISPR/Cas9 effector has also been
utilized in biosensing applications. The recent discovery of the collateral RNA cleavage …

Opportunities and challenges for biosensors and nanoscale analytical tools for pandemics: COVID-19

N Bhalla, Y Pan, Z Yang, AF Payam - ACS nano, 2020 - ACS Publications
Biosensors and nanoscale analytical tools have shown huge growth in literature in the past
20 years, with a large number of reports on the topic of 'ultrasensitive','cost-effective', and …

Development of point-of-care biosensors for COVID-19

JR Choi - Frontiers in chemistry, 2020 - frontiersin.org
Coronavirus disease 2019 (COVID-19) outbreak has become a global pandemic. The
deleterious effects of coronavirus have prompted the development of diagnostic tools to …

Turning the page: advancing paper-based microfluidics for broad diagnostic application

MM Gong, D Sinton - Chemical reviews, 2017 - ACS Publications
Infectious diseases are a major global health issue. Diagnosis is a critical first step in
effectively managing their spread. Paper-based microfluidic diagnostics first emerged in …

Point-of-care diagnostics: recent developments in a connected age

S Nayak, NR Blumenfeld, T Laksanasopin… - Analytical …, 2017 - ACS Publications
The field of point-of-care (POC) diagnostics offers the tantalizing possibility of providing
rapid diagnostic results in nonlaboratory settings. Here, we review progress in this research …

Graphene biosensors for bacterial and viral pathogens

Z Jiang, B Feng, J Xu, T Qing, P Zhang… - Biosensors and …, 2020 - Elsevier
The infection and spread of pathogens (eg, COVID-19) pose an enormous threat to the
safety of human beings and animals all over the world. The rapid and accurate monitoring …

Advances in point-of-care nucleic acid extraction technologies for rapid diagnosis of human and plant diseases

R Paul, E Ostermann, Q Wei - Biosensors and bioelectronics, 2020 - Elsevier
Global health and food security constantly face the challenge of emerging human and plant
diseases caused by bacteria, viruses, fungi, and other pathogens. Disease outbreaks such …

Fully integrated microfluidic devices for qualitative, quantitative and digital nucleic acids testing at point of care

Z Li, Y Bai, M You, J Hu, C Yao, L Cao, F Xu - Biosensors and …, 2021 - Elsevier
Benefiting from emerging miniaturized and equipment-free nucleic acid testing (NAT)
technologies, fully integrated NAT devices at point of care (POC) with the capability of …