Importance Malignant primary brain tumors cause more than 15 000 deaths per year in the
United States. The annual incidence of primary malignant brain tumors is approximately 7 …

The purpose of this review is to provide a sufficiently detailed perspective on epidemiologic
studies of primary brain tumors to encourage multidisciplinary etiologic and prognostic …

Objective: Because the d-2-hydroxyglutarate (D2HG) product of mutant isocitrate
dehydrogenase 1 (IDH1mut) is released by tumor cells into the microenvironment and is …

Seizures are common in patients with brain tumors, and epilepsy can significantly impact
patient quality of life. Therefore, a thorough understanding of rates and predictors of …

Object Seizures play an important role in the clinical presentation and postoperative quality
of life of patients who undergo surgical resection of low-grade gliomas (LGGs). The aim of …

Seizures and epilepsy are common sequelae of acute brain insults such as stroke, traumatic
brain injury, and central nervous system infections. Early, or acute symptomatic, seizures …

Epilepsy is most likely to develop in later life. The burden of this disorder on health-care
resources will rise further as the world's population continues to age. Making a secure …

Brain gliomas are highly epileptogenic. Excitatory glutamatergic mechanisms are involved in
the generation of epileptic activities in the neocortex surrounding gliomas. However …

Seizure is a common presenting manifestation and plays an important role in the clinical
presentation and quality of life for patients with low-grade gliomas (LGGs). The authors set …

BACKGROUND: The ideal treatment strategy for low-grade gliomas (LGGs) is a
controversial topic. Additionally, only smaller single-center series dealing with the concept of …