[HTML][HTML] The biology, function, and applications of exosomes in cancer

J Liu, L Ren, S Li, W Li, X Zheng, Y Yang, W Fu… - … Pharmaceutica Sinica B, 2021 - Elsevier
Exosomes are cell-derived nanovesicles with diameters from 30 to 150 nm, released upon
fusion of multivesicular bodies with the cell surface. They can transport nucleic acids …

Circulating biomarkers in patients with glioblastoma

J Müller Bark, A Kulasinghe, B Chua, BW Day… - British journal of …, 2020 - nature.com
Gliomas are the most common tumours of the central nervous system and the most
aggressive form is glioblastoma (GBM). Despite advances in treatment, patient survival …

Therapeutic and diagnostic potential of exosomes as drug delivery systems in brain cancer

DI Avgoulas, KS Tasioulis, RM Papi, AA Pantazaki - Pharmaceutics, 2023 - mdpi.com
Cancer is designated as one of the principal causes of mortality universally. Among different
types of cancer, brain cancer remains the most challenging one due to its aggressiveness …

The function of astrocyte mediated extracellular vesicles in central nervous system diseases

T Gharbi, Z Zhang, GY Yang - Frontiers in cell and developmental …, 2020 - frontiersin.org
Astrocyte activation plays an important role during disease-induced inflammatory response
in the brain. Exosomes in the brain could be released from bone marrow (BM)-derived stem …

Emerging prospects of extracellular vesicles for brain disease theranostics

R Wang, X Wang, Y Zhang, H Zhao, J Cui, J Li… - Journal of Controlled …, 2022 - Elsevier
In the past decade, bio-nanoparticles inspired by nature with advantageous properties have
attracted extensive interest for accurate diagnosis and effective treatment. Extracellular …

Exosome-packaged miR-1246 contributes to bystander DNA damage by targeting LIG4

LJ Mo, M Song, QH Huang, H Guan, XD Liu… - British journal of …, 2018 - nature.com
Background An increasing number of studies have recently reported that microRNAs
packaged in exosomes contribute to multiple biological processes such as cancer …

Extracellular vesicles: The key for precision medicine in glioblastoma

M Del Bene, D Osti, S Faletti, GV Beznoussenko… - Neuro …, 2022 - academic.oup.com
Glioblastoma (GBM) represents the most aggressive and lethal disease of the central
nervous system. Diagnosis is delayed following the occurrence of symptoms, and treatment …

Exosomes as novel diagnostic biomarkers and therapeutic tools in gliomas

P Skouras, AN Gargalionis, C Piperi - International Journal of Molecular …, 2023 - mdpi.com
Exosomes constitute small extracellular vesicles that contain lipids, proteins, nucleic acids,
and glycoconjugates from the secreted cells and are capable of transmitting signals …

The exosome journey: from biogenesis to regulation and function in cancers

Y Li, L Meng, B Li, Y Li, T Shen, B Zhao - Journal of Oncology, 2022 - Wiley Online Library
Exosomes are a type of small endosomal‐derived vesicles ranging from 30 to 150 nm,
which can serve as functional mediators in cell‐to‐cell communication and various …

[HTML][HTML] Role of exosomes in the progression, diagnosis, and treatment of gliomas

J Shi, Y Zhang, B Yao, P Sun, Y Hao… - … medical journal of …, 2020 - ncbi.nlm.nih.gov
Gliomas are the most common primary malignant brain tumors associated with a low
survival rate. Even after surgery, radiotherapy, and chemotherapy, gliomas still have a poor …