Methotrexate (MTX) is the central drug in the management of rheumatoid arthritis (RA) and
other immune mediated inflammatory diseases. It is widely used either in monotherapy or in …

Background Methotrexate is routinely used in the treatment of inflammatory arthritis. There
have been concerns regarding the safety of using concurrent non‐steroidal anti …

Background Methotrexate is the most frequently used first-line antirheumatic drug. We report
the findings of a phase 3 study of monotherapy with tofacitinib, an oral Janus kinase …

Objectives. To assess the risk of severe infections associated with the use of traditional
disease-modifying anti-rheumatic drugs (DMARDs) and glucocorticoid agents in rheumatoid …

Background Methotrexate is the preferred initial disease-modifying antirheumatic drug
(DMARD) for rheumatoid arthritis (RA). However, clinically useful tools for individualized …

OBJECTIVES: To examine the prevalence and effect of multimorbidity on health-related
quality of life (HRQoL) and daily functioning in the general population, and to analyze the …

The programmed cell death 1 (PD-1) receptor plays a major role in regulating T cell
activation. Our aim was to determine how inflammation influences PD-1-mediated T cell …

Abstract Treat-to-target (T2T) is currently the most fashionable strategy for treatment-naïve,
early rheumatoid arthritis (RA) patients. A T2T approach can lead to a complete and drug …

Ethnopharmacological relevance Large-scale study of traditional Chinese medicine (TCM)
usage among patients with rheumatoid arthritis (RA) is lacking. The aim of this study is to …

The aim of the study was to identify the determinants of adherence to medication among
Egyptian patients with SLE. A single-center cross-sectional study was conducted among …