[HTML][HTML] Polymeric micelles in drug delivery: An insight of the techniques for their characterization and assessment in biorelevant conditions

M Ghezzi, S Pescina, C Padula, P Santi… - Journal of Controlled …, 2021 - Elsevier
Polymeric micelles, ie aggregation colloids formed in solution by self-assembling of
amphiphilic polymers, represent an innovative tool to overcome several issues related to …

Nanocarrier drug delivery systems: characterization, limitations, future perspectives and implementation of artificial intelligence

SZ Alshawwa, AA Kassem, RM Farid, SK Mostafa… - Pharmaceutics, 2022 - mdpi.com
There has been an increasing demand for the development of nanocarriers targeting
multiple diseases with a broad range of properties. Due to their tiny size, giant surface area …

Blood-brain barrier–penetrating single CRISPR-Cas9 nanocapsules for effective and safe glioblastoma gene therapy

Y Zou, X Sun, Q Yang, M Zheng, O Shimoni… - Science …, 2022 - science.org
We designed a unique nanocapsule for efficient single CRISPR-Cas9 capsuling,
noninvasive brain delivery and tumor cell targeting, demonstrating an effective and safe …

The in vivo fate of polymeric micelles

Y Cai, J Qi, Y Lu, H He, W Wu - Advanced Drug Delivery Reviews, 2022 - Elsevier
This review aims to provide a systemic analysis of the in vivo, as well as subcellular, fate of
polymeric micelles (PMs), starting from the entry of PMs into the body. Few PMs are able to …

Application of carbon-based quantum dots in photodynamic therapy

A Karagianni, NG Tsierkezos, M Prato, M Terrones… - Carbon, 2023 - Elsevier
Photodynamic Therapy (PDT) is a non-invasive therapeutic modality that can treat a wide
variety of cancer types by means of photosensitizer drug, light, and oxygen. Due to …

Synthesis and Bioapplications of Ag2S Quantum Dots with Near‐Infrared Fluorescence

C Ding, Y Huang, Z Shen, X Chen - Advanced Materials, 2021 - Wiley Online Library
Quantum dots (QDs) with near‐infrared fluorescence (NIR) are an emerging class of QDs
with unique capabilities owing to the deeper tissue penetrability of NIR light compared with …

New perspective of the ternary complex of nano-curcumin with β-lactoglobulin in the presence of α-lactalbumin: Spectroscopic and molecular dynamic investigations

M Tabasi, P Maghami, Z Amiri-Tehranizadeh… - Journal of Molecular …, 2023 - Elsevier
Understanding the interaction between nano-curcumin (Nano Cur) and proteins is essential
for elucidating the potential therapeutic applications of curcumin in nano formulations. In this …

Lipid polymer hybrid nanoparticles: a custom-tailored next-generation approach for cancer therapeutics

KR Gajbhiye, R Salve, M Narwade, A Sheikh… - Molecular Cancer, 2023 - Springer
Lipid-based polymeric nanoparticles are the highly popular carrier systems for cancer drug
therapy. But presently, detailed investigations have revealed their flaws as drug delivery …

Absorption, distribution, metabolism, and excretion of nanocarriers in vivo and their influences

A Zhang, K Meng, Y Liu, Y Pan, W Qu, D Chen… - Advances in Colloid and …, 2020 - Elsevier
As one of the most promising and effective delivery systems for targeted controlled-release
drugs, nanocarriers (NCs) have been widely studied. Although the development of …

Nanocarrier‐mediated cytosolic delivery of biopharmaceuticals

W He, X Xing, X Wang, D Wu, W Wu… - Advanced functional …, 2020 - Wiley Online Library
Biopharmaceuticals have emerged to play a vital role in disease treatment and have shown
promise in the rapidly expanding pharmaceutical market due to their high specificity and …