The chemistry of heterocycles in the 21st century

VN Charushin, EV Verbitskiy, ON Chupakhin… - Uspekhi Khimii, 2024 - mathnet.ru
The chemistry of heterocyclic compounds has traditionally been and remains a bright area of
chemical science in Russia. This is due to the fact that many heterocycles find the widest …

Recent advances in the chemistry of thieno[2,3-b]pyridines 1. Methods of synthesis of thieno[2,3-b]pyridines

VV Dotsenko, DS Buryi, DY Lukina… - Russian Chemical …, 2020 - Springer
Recent advances in the chemistry of thieno[2,3-b]pyridines 1. Methods of synthesis of thieno[2,3-b]pyridines
| Russian Chemical Bulletin Skip to main content SpringerLink Account Menu Find a journal …

Heterocyclization reactions using malononitrile dimer (2-aminopropene-1, 1, 3-tricarbonitrile)

VV Dotsenko, SG Krivokolysko… - Chemistry of Heterocyclic …, 2018 - Springer
In this work, we provide the first generalized and critical analysis of data on the chemistry of
malononitrile dimer (2-aminopropene-1, 1, 3-tricarbonitrile)–a multifunctional reagent that is …

Access to molecular complexity. Multicomponent reactions involving five or more components

VG Nenajdenko - Russian Chemical Reviews, 2020 - iopscience.iop.org
The evaluation of the significance of a chemical transformation addresses many factors,
including such important characteristics as the number of chemical bonds formed in one …

Synthesis and analgesic activity of new heterocyclic cyanothioacetamide derivatives

IV Bibik, EY Bibik, VV Dotsenko, KA Frolov… - Russian Journal of …, 2021 - Springer
The reaction of cyanothioacetamide with aromatic aldehydes and 1, 3-dicarbonyl
compounds followed by aminomethylation or S-alkylation gave a series of heterocyclic …

New possibilities of the Mannich reaction in the synthesis of N-, S,N-, and Se,N-heterocycles

VV Dotsenko, KA Frolov, EA Chigorina… - Russian chemical …, 2019 - Springer
The review summarizes the results obtained by our research group over the past 15 years in
chemistry of N-, S, N-, and Se, N-heterocycles resulted from aminomethlation of a wide …

The reactions of N, N′-diphenyldithiomalondiamide with arylmethylidene Meldrum's acids

VV Dotsenko, AV Aksenov, AE Sinotsko… - International Journal of …, 2022 - mdpi.com
The Michael addition reaction between dithiomalondianilide (N, N′-
diphenyldithiomalondiamide) and arylmethylidene Meldrum's acids, accompanied by …

Synthesis and Properties of 4,6-Dimethyl-5-pentyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile and 3-Amino-4,6-dimethyl-5-pentylthieno[2,3-b]pyridines

DS Buryi, VV Dotsenko, NA Aksenov… - Russian Journal of …, 2019 - Springer
Abstract The reaction of 3-pentylpentane-2, 4-dione with cyanothioacetamide afforded 4, 6-
dimethyl-5-pentyl-2-thioxo-1, 2-dihydropyridine-3-carbonitrile. Alkylation of the latter led to …

New 2-oxopyridine/2-thiopyridine derivatives tethered to a benzotriazole with cytotoxicity on MCF7 cell lines and with antiviral activities

AM Attia, AI Khodair, EA Gendy… - Letters in Drug …, 2020 - ingentaconnect.com
Background: Perturbation of nucleic acids structures and confirmation by small molecules
through intercalation binding is an intriguing application in anticancer therapy. The planar …

Water/Alkali-catalyzed reactions of azides with 2-cyanothioacetamides. eco-friendly synthesis of monocyclic and bicyclic 1, 2, 3-thiadiazole-4-carbimidamides and 5 …

VO Filimonov, LN Dianova, TV Beryozkina… - The Journal of …, 2019 - ACS Publications
The reactions of thioamides with azides in water were studied. It was reliably shown that the
reaction of 2-cyanothioacetamides 1 with various types of azides 2 in water in the presence …