Novel antimicrobial agents for combating antibiotic-resistant bacteria
Antibiotic therapy has become increasingly ineffective against bacterial infections due to the
rise of resistance. In particular, ESKAPE pathogens (Enterococcus faecium, Staphylococcus …
rise of resistance. In particular, ESKAPE pathogens (Enterococcus faecium, Staphylococcus …
Galleria mellonella as a Suitable Model of Bacterial Infection: Past, Present and Future
G Ménard, A Rouillon, V Cattoir… - Frontiers in cellular and …, 2021 - frontiersin.org
The increasing interest for Galleria mellonella larvae as an infection model is evidenced by
the number of papers reporting its use, which increases exponentially since the early 2010s …
the number of papers reporting its use, which increases exponentially since the early 2010s …
Galleria mellonella as an infection model: an in-depth look at why it works and practical considerations for successful application
MF Pereira, CC Rossi, GC da Silva… - Pathogens and …, 2020 - academic.oup.com
The larva of the greater wax moth Galleria mellonella is an increasingly popular model for
assessing the virulence of bacterial pathogens and the effectiveness of antimicrobial agents …
assessing the virulence of bacterial pathogens and the effectiveness of antimicrobial agents …
Biological challenges of phage therapy and proposed solutions: a literature review
Introduction: In light of the emergence of antibiotic-resistant bacteria, phage (bacteriophage)
therapy has been recognized as a potential alternative or addition to antibiotics in Western …
therapy has been recognized as a potential alternative or addition to antibiotics in Western …
Advances in bacteriophage therapy against relevant multidrug-resistant pathogens
A Broncano-Lavado, G Santamaría-Corral, J Esteban… - Antibiotics, 2021 - mdpi.com
The increase of multiresistance in bacteria and the shortage of new antibiotics in the market
is becoming a major public health concern. The World Health Organization (WHO) has …
is becoming a major public health concern. The World Health Organization (WHO) has …
Phage resistance formation and fitness costs of hypervirulent Klebsiella pneumoniae mediated by K2 capsule-specific phage and the corresponding mechanisms
M Tang, Z Huang, X Zhang, J Kong, B Zhou… - Frontiers in …, 2023 - frontiersin.org
Introduction Phage is promising for the treatment of hypervirulent Klebsiella pneumoniae
(hvKP) infections. Although phage resistance seems inevitable, we found that there still was …
(hvKP) infections. Although phage resistance seems inevitable, we found that there still was …
Identification of three capsule depolymerases in a bacteriophage infecting Klebsiella pneumoniae capsular types K7, K20, and K27 and therapeutic application
JW Wu, JT Wang, TL Lin, YZ Liu, LT Wu… - Journal of Biomedical …, 2023 - Springer
Background Klebsiella pneumoniae capsular types K1, K2, K5, K20, K54, and K57 are
prevalent hypervirulent types associated with community infections, and worrisomely …
prevalent hypervirulent types associated with community infections, and worrisomely …
Novel Klebsiella pneumoniae K23-Specific Bacteriophages From Different Families: Similarity of Depolymerases and Their Therapeutic Potential
RB Gorodnichev, NV Volozhantsev… - Frontiers in …, 2021 - frontiersin.org
Antibiotic resistance is a major public health concern in many countries worldwide. The
rapid spread of multidrug-resistant (MDR) bacteria is the main driving force for the …
rapid spread of multidrug-resistant (MDR) bacteria is the main driving force for the …
Microbiology's next top model: Galleria in the molecular age
Galleria mellonella has risen to fame as an invertebrate model organism given its ethical
advantages, low maintenance costs, rapid reproduction time, short life cycle, high number of …
advantages, low maintenance costs, rapid reproduction time, short life cycle, high number of …
Emerging strategies to combat β-lactamase producing ESKAPE pathogens
Since the discovery of penicillin by Alexander Fleming in 1929 as a therapeutic agent
against staphylococci, β-lactam antibiotics (BLAs) remained the most successful antibiotic …
against staphylococci, β-lactam antibiotics (BLAs) remained the most successful antibiotic …