Nanomaterials for the treatment and diagnosis of Alzheimer's disease: an overview

M Bilal, M Barani, F Sabir, A Rahdar, GZ Kyzas - NanoImpact, 2020 - Elsevier
Alzheimer's disease (AD) is a chronic neurodegenerative disorder associated with
dementia. To overcome the limitations of diagnosis and treatment nanotechnology research …

Chemical sensing platforms for detecting trace-level Alzheimer's core biomarkers

K Kim, CH Lee, CB Park - Chemical Society Reviews, 2020 - pubs.rsc.org
Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder and affects more
than 10% of the population aged over 65 worldwide. Despite considerable global efforts, AD …

A label-free biosensor based on graphene and reduced graphene oxide dual-layer for electrochemical determination of beta-amyloid biomarkers

J Sethi, M Van Bulck, A Suhail, M Safarzadeh… - Microchimica Acta, 2020 - Springer
A label-free biosensor is developed for the determination of plasma-based Aβ 1–42
biomarker in Alzheimer's disease (AD). The platform is based on highly conductive dual …

Nanomaterials towards biosensing of Alzheimer's disease biomarkers

P Carneiro, S Morais, MC Pereira - Nanomaterials, 2019 - mdpi.com
Alzheimer's disease (AD) is an incurable and highly debilitating condition characterized by
the progressive degeneration and/or death of nerve cells, which leads to manifestation of …

Tailored biofunctionalized biosensor for the label-free sensing of prostate-specific antigen

S Mishra, ES Kim, PK Sharma, ZJ Wang… - ACS Applied Bio …, 2020 - ACS Publications
The increase in the demand and popularity of smart biosensors has brought a novel and
innovative concept to develop a diverse range of semen mutual biomarker (ie, prostate …

Amyloid-beta peptide detection via aptamer-functionalized nanowire sensors exploiting single-trap phenomena

Y Kutovyi, H Hlukhova, N Boichuk, M Menger… - Biosensors and …, 2020 - Elsevier
New highly sensitive direct methods for the early detection of peptides involved in
Alzheimer's disease (AD) are required in order to prolong effective and healthy memory and …

Graphene-based enzyme-modified field-effect transistor biosensor for monitoring drug effects in Alzheimer's disease treatment

MS Chae, YK Yoo, J Kim, TG Kim, KS Hwang - Sensors and Actuators B …, 2018 - Elsevier
A reduced graphene oxide-based enzyme-modified field-effect transistor (RGO-EnFET) was
fabricated to study the enzymatic kinetics between acetylcholinesterase (AChE) and …

Biosensors on the road to early diagnostic and surveillance of Alzheimer's disease

P Carneiro, S Morais, M do Carmo Pereira - Talanta, 2020 - Elsevier
Alzheimer's disease is a debilitating and largely untreatable condition with subtle onset and
slow progression over an extensive period of time, which culminate in increasing levels of …

Recent progress and challenges in the application of molecularly imprinted polymers for early-stage screening of neurodegenerative diseases-related protein …

M Adampourezare, M Hasanzadeh, B Nikzad - Microchemical Journal, 2023 - Elsevier
Proteomics is an essential technology in medicine and biotechnology. Protein profiling and
its application in disease diagnosis have attracted a lot of attention from scientists. Highly …

Spatial organization of protein aggregates on red blood cells as physical biomarkers of Alzheimer's disease pathology

PN Nirmalraj, T Schneider, A Felbecker - Science advances, 2021 - science.org
Quantifying physical differences of protein aggregates implicated in Alzheimer's disease
(AD), in blood, could provide crucial information on disease stages. Here, red blood cells …