Sesquiterpene lactones constitute a major class of bioactive natural products. One of the
naturally occurring sesquiterpene lactones is costunolide, which has been extensively …

Vernonia amygdalina has been a known food and medicinal plants used in Asia and Africa
(West Africa) due to its pharmacological effects (antioxidant, anti-diabetes, antiinflammatory …

There are 300 known Saussurea species. Among them, Saussurea lappa (S. lappa) is a
representative perennial herb, globally distributed across Himalaya region. S. lappa has …

Costunolide (CE) and dehydrocostuslactone (DE) are derived from many species of
medicinal plants, such as Saussurea lappa Decne and Laurus nobilis L. They have been …

Since ancient times, plant roots have been widely used in traditional medicine for treating
various ailments and diseases due to their beneficial effects. A large number of studies have …

Abstract Background Costus speciosus (Koen ex. Retz.) Sm (Costaceae) is an Indian
ornamental plant which has long been used medicinally in traditional systems of medicine …

The sesquiterpene costunolide has a broad range of biological activities and is the parent
compound for many other biologically active sesquiterpenes such as parthenolide. Two …

The goal of this study was to investigate the effects of three different extracts of Saussurea
costus roots (ethanol, methanol, and water) as a food additive in alleviating the harmful …

Candida albicans infections are threatening public health but there are only several
antifungal drugs available. This study was to assess the effects of dehydrocostus lactone …

Despite the availability of several therapeutic options, a safer and more effective modality is
urgently needed for treatment of bladder cancer. Costunolide, a member of sesquiterpene …