Cancer health disparities in racial/ethnic minorities in the United States

VA Zavala, PM Bracci, JM Carethers… - British journal of …, 2021 - nature.com
There are well-established disparities in cancer incidence and outcomes by race/ethnicity
that result from the interplay between structural, socioeconomic, socio-environmental …

Promoting inclusion in clinical trials—a rapid review of the literature and recommendations for action

DH Bodicoat, AC Routen, A Willis, W Ekezie, C Gillies… - Trials, 2021 - Springer
Background Without inclusion of diverse research participants, it is challenging to
understand how study findings will translate into the real world. Despite this, a lack of …

Increasing racial and ethnic diversity in cancer clinical trials: an American Society of Clinical Oncology and Association of Community Cancer Centers joint research …

RA Oyer, P Hurley, L Boehmer… - Journal of Clinical …, 2022 - ascopubs.org
A concerted commitment across research stakeholders is necessary to increase equity,
diversity, and inclusion (EDI) and address barriers to cancer clinical trial recruitment and …

FDA approval summary: accelerated approval of sacituzumab govitecan-hziy for third-line treatment of metastatic triple-negative breast cancer

S Wahby, L Fashoyin-Aje, CL Osgood, J Cheng… - Clinical Cancer …, 2021 - AACR
Abstract On April 22, 2020, the FDA granted accelerated approval to sacituzumab govitecan-
hziy (TRODELVY; Immunomedics, Inc.) for the treatment of patients with metastatic triple …

Cancer healthcare disparities among African Americans in the United States

E Mitchell, OB Alese, C Yates, BM Rivers… - Journal of the National …, 2022 - Elsevier
A need exists to examine racial disparities in the healthcare arena and the impact on
patients with cancer. Despite ongoing efforts to increase equity in primary healthcare …

Interventions to increase racial and ethnic minority accrual into cancer clinical trials: a systematic review

R Nouvini, PA Parker, CD Malling, K Godwin… - Cancer, 2022 - Wiley Online Library
Background Racial and ethnic minorities (REMs) continue to be underrepresented in clinical
trials despite the 1993 National Institutes of Health's Revitalization Act mandating the …

Perceived institutional barriers among clinical and research professionals: minority participation in oncology clinical trials

SJ Niranjan, JA Wenzel, MY Martin, MN Fouad… - JCO Oncology …, 2021 - ascopubs.org
PURPOSE: In general, participation rates in cancer clinical trials are very low. However,
participation rates are especially low among the socially disadvantaged and racial and …

Development of an actionable framework to address cancer care disparities in medically underserved populations in the United States: expert roundtable …

KM Winkfield, JM Regnante, E Miller-Sonet… - JCO Oncology …, 2021 - ascopubs.org
PURPOSE: Cancer disparities persist among medically underserved populations despite
widespread efforts to address them. We describe the development of a framework for …

Participation of Black US residents in clinical trials of 24 cardiovascular drugs granted FDA approval, 2006-2020

S Chen, J Li - JAMA Network Open, 2021 - jamanetwork.com
Although mortality from cardiovascular disease (CVD) has declined consistently in the
United States, CVD remains a major public health burden for Black US residents. 1, 2 Given …

Are ethnic and racial minority women less likely to participate in clinical trials?

SN Patel, JN Staples, C Garcia, L Chatfield… - Gynecologic …, 2020 - Elsevier
Objectives Given the disparity that exists in enrollment of minorities to oncology clinical trials,
the objective of our study was to assess whether race is associated with willingness to …