[HTML][HTML] Mechanisms of ultrafine particle-induced respiratory health effects

GD Leikauf, SH Kim, AS Jang - Experimental & molecular medicine, 2020 - nature.com
Particulate matter (PM) is the principal component of air pollution. PM includes a range of
particle sizes, such as coarse, fine, and ultrafine particles. Particles that are< 100 nm in …

[HTML][HTML] Overview of the mechanisms of oxidative stress: impact in inflammation of the airway diseases

GD Albano, RP Gagliardo, AM Montalbano, M Profita - Antioxidants, 2022 - mdpi.com
Inflammation of the human lung is mediated in response to different stimuli (eg, physical,
radioactive, infective, pro-allergenic or toxic) such as cigarette smoke and environmental …

[HTML][HTML] Aryl hydrocarbon receptor in oxidative stress as a double agent and its biological and therapeutic significance

AY Grishanova, ML Perepechaeva - International Journal of Molecular …, 2022 - mdpi.com
The aryl hydrocarbon receptor (AhR) has long been implicated in the induction of a battery
of genes involved in the metabolism of xenobiotics and endogenous compounds. AhR is a …

Oxidative stress in chronic lung disease: From mitochondrial dysfunction to dysregulated redox signaling

A van der Vliet, YMW Janssen-Heininger… - Molecular aspects of …, 2018 - Elsevier
The lung is a delicate organ with a large surface area that is continuously exposed to the
external environment, and is therefore highly vulnerable to exogenous sources of oxidative …

[HTML][HTML] Recent developments in the role of reactive oxygen species in allergic asthma

J Qu, Y Li, W Zhong, P Gao, C Hu - Journal of thoracic disease, 2017 - ncbi.nlm.nih.gov
Allergic asthma has a global prevalence, morbidity, and mortality. Many environmental
factors, such as pollutants and allergens, are highly relevant to allergic asthma. The most …

A new look at the pathogenesis of asthma

ST Holgate, HS Arshad, GC Roberts… - Clinical …, 2010 - portlandpress.com
Asthma is an inflammatory disorder of the conducting airways that has strong association
with allergic sensitization. The disease is characterized by a polarized Th-2 (T-helper-2) …

Does outdoor air pollution induce new cases of asthma? Biological plausibility and evidence; a review

AM Gowers, P Cullinan, JG Ayres, HR Anderson… - …, 2012 - Wiley Online Library
It is widely accepted that air pollution can exacerbate asthma in those who already have the
condition. What is less clear is whether air pollution can contribute to the initiation of new …

[HTML][HTML] Oxidative stress and inflammation in acute and chronic lung injuries

FS Bezerra, M Lanzetti, RT Nesi, AC Nagato, CP Silva… - Antioxidants, 2023 - mdpi.com
Acute and chronic lung injuries are among the leading causes of mortality worldwide. Lung
injury can affect several components of the respiratory system, including the airways …

[HTML][HTML] Mechanistic impact of outdoor air pollution on asthma and allergic diseases

SK Huang, Q Zhang, Z Qiu, KF Chung - Journal of thoracic disease, 2015 - ncbi.nlm.nih.gov
Over the past decades, asthma and allergic diseases, such as allergic rhinitis and eczema,
have become increasingly common, but the reason for this increased prevalence is still …

Toxicity of zinc oxide (ZnO) nanoparticles on human bronchial epithelial cells (BEAS-2B) is accentuated by oxidative stress

BC Heng, X Zhao, S Xiong, KW Ng, FYC Boey… - Food and Chemical …, 2010 - Elsevier
Although several studies reported that cytotoxic effects of various nanoparticles are partially
due to induction of oxidative stress, it is unclear how oxidative state of the cell per se could …