Respiratory syncytial virus—a comprehensive review

AT Borchers, C Chang, ME Gershwin… - Clinical reviews in allergy …, 2013 - Springer
Respiratory syncytial virus (RSV) is amongst the most important pathogenic infections of
childhood and is associated with significant morbidity and mortality. Although there have …

The common cold

T Heikkinen, A Järvinen - The Lancet, 2003 - thelancet.com
Despite great advances in medicine, the common cold continues to be a great burden on
society in terms of human suffering and economic losses. Of the several viruses that cause …

Eosinophils: biological properties and role in health and disease

SP Hogan, HF Rosenberg, R Moqbel… - Clinical & …, 2008 - Wiley Online Library
Eosinophils are pleiotropic multifunctional leukocytes involved in initiation and propagation
of diverse inflammatory responses, as well as modulators of innate and adaptive immunity …

Mechanisms of eosinophil-associated inflammation

GJ Gleich - Journal of Allergy and Clinical Immunology, 2000 - Elsevier
Increasing evidence supports a critical role for the eosinophil in disease. Here, the
mechanisms underlying eosinophil-associated inflammation are reviewed including …

Activation of airway epithelial cells by toll-like receptor agonists

Q Sha, AQ Truong-Tran, JR Plitt, LA Beck… - American journal of …, 2004 - atsjournals.org
Toll-like receptors (TLR) play an important role in pathogen recognition and innate immunity.
We investigated the presence and function of TLRs in the BEAS-2B airway epithelial cell line …

Vaccination strategies for mucosal immune responses

PL Ogra, H Faden, RC Welliver - Clinical microbiology reviews, 2001 - Am Soc Microbiol
Mucosal administration of vaccines is an important approach to the induction of appropriate
immune responses to microbial and other environmental antigens in systemic sites and …

Respiratory syncytial virus infection: immune response, immunopathogenesis, and treatment

JB Domachowske, HF Rosenberg - Clinical Microbiology Reviews, 1999 - Am Soc Microbiol
Respiratory syncytial virus (RSV) is the single most important cause of lower respiratory tract
infection during infancy and early childhood. Once RSV infection is established, the host …

Respiratory syncytial virus

CB Hall - Principles and practice of clinical virology, 1999 - Wiley Online Library
Respiratory synctial virus (RSV) infections are a common and concerning conundrum. This
ubiquitous agent is the major respiratory pathogen of young children, with life‐threatening …

Recombinant human eosinophil-derived neurotoxin/RNase 2 functions as an effective antiviral agent against respiratory syncytial virus

JB Domachowske, KD Dyer, CA Bonville… - Journal of Infectious …, 1998 - academic.oup.com
A dose-dependent decrease in infectivity was observed on introduction of eosinophils into
suspensions of respiratory syncytial virus group B (RSV-B). This antiviral effect was reversed …

Role of chemokines in the pathogenesis of asthma

NW Lukacs - Nature Reviews Immunology, 2001 - nature.com
The prevalence of asthma has risen drastically in the last two decades, with a worldwide
impact on health care systems. Although several factors contribute to the development of …