DNA methylation is the most well studied of the epigenetic regulators in relation to
environmental exposures. To date, numerous studies have detailed the manner by which …

Arsenic intoxication represents a worldwide health problem and occurs mainly through
drinking water. Arsenic, a metalloid and naturally occurring element, is one of the most …

Environmental exposure is an important but underappreciated risk factor contributing to the
development and severity of cardiovascular disease (CVD). The heart and vascular system …

Arsenic toxicity is a worldwide health concern as several millions of people are exposed to
this toxicant via drinking water, and exposure affects almost every organ system in the body …

Worldwide, more than 200 million people are estimated to be exposed to unsafe levels of
arsenic. Chronic exposure to unsafe levels of groundwater arsenic is responsible for …

Epigenome-wide association studies of disease widely use DNA methylation measured in
blood as a surrogate tissue. Cell proportions can vary between people and confound …

Background: Characterization of the epigenome is a primary interest for children's
environmental health researchers studying the environmental influences on human …

Background: Exposure to inorganic and organic arsenic compounds is a major public health
problem that affects hundreds of millions of people worldwide. Exposure to arsenic is …

Background Recent interest in reference-free deconvolution of DNA methylation data has
led to several supervised methods, but these methods do not easily permit the interpretation …

Epidemiological studies have demonstrated that genetic, environmental, behavioral, and
clinical factors contribute to cardiovascular disease development. How these risk factors …