Weil's Disease—Immunopathogenesis, Multiple Organ Failure, and Potential Role of Gut Microbiota

P Petakh, V Isevych, A Kamyshnyi, V Oksenych - Biomolecules, 2022 - mdpi.com
Leptospirosis is an important zoonotic disease, causing about 60,000 deaths annually. In
this review, we have described in detail the immunopathogenesis of leptospirosis, the …

A dual pharmacological strategy against COVID-19: The therapeutic potential of metformin and atorvastatin

LA De Jesús-González, RM Del Ángel… - Microorganisms, 2024 - mdpi.com
Metformin (MET) and atorvastatin (ATO) are promising treatments for COVID-19. This review
explores the potential of MET and ATO, commonly prescribed for diabetes and dyslipidemia …

Metformin therapy changes gut microbiota alpha-diversity in COVID-19 patients with type 2 diabetes: the role of SARS-CoV-2 variants and antibiotic treatment

P Petakh, I Kamyshna, V Oksenych, D Kainov… - Pharmaceuticals, 2023 - mdpi.com
The gut microbiota play a crucial role in maintaining host health and have a significant
impact on human health and disease. In this study, we investigated the alpha diversity of gut …

Exploring Paxlovid Efficacy in COVID-19 Patients with MAFLD: Insights from a Single-Center Prospective Cohort Study

M Buchynskyi, V Oksenych, I Kamyshna, O Kamyshnyi - Viruses, 2024 - mdpi.com
This study investigates the intricate interplay between Metabolic-associated Fatty Liver
Disease (MAFLD) and COVID-19, exploring the impact of MAFLD on disease severity …

Metformin Alters mRNA Expression of FOXP3, RORC, and TBX21 and Modulates Gut Microbiota in COVID-19 Patients with Type 2 Diabetes

P Petakh, I Kamyshna, V Oksenych, O Kamyshnyi - Viruses, 2024 - mdpi.com
COVID-19 remains a significant global concern, particularly for individuals with type 2
diabetes who face an elevated risk of hospitalization and mortality. Metformin, a primary …